Core A: Administrative Core

该形成中心的主要目标是组建一个多学科专家团队， 我们对双酚A和邻苯二甲酸酯暴露对人类发育风险的认识存在重大差距。 我们将积极让初级研究人员参与这项研究工作，并积极交流我们的研究 向卫生保健界和公众提供调查结果。研究工作的核心将是两个试点 人类队列研究：在伊利诺伊州厄巴纳-香槟招募的出生队列（S。Schantz，PI）和 青少年队列作为正在进行的研究的一部分在新贝德福德，MA（S。Korrick，PI）。的 形成中心还将包括实验室动物项目（J. Juraska，PI和H。姚明，PI） 这些人群中暴露的时间。 该行政核心将组织和促进整个研究计划，包括监督， 协调和整合所有与中心有关的活动。这将包括组织和安排 内部咨询委员会每月会议和中心联合实验室每月会议 研究人员，组织中心科学家与六名成员的外部咨询委员会的年度会议， 委员会，协调社区参与活动，并与儿科健康 专家为儿科医疗保健社区的人翻译相关信息。统计 两项人类队列试验研究（项目1和2）的支持将通过一项研究计划提供给Dr. 密歇根州立大学的约瑟夫加德纳，这将通过行政核心管理。作为 形成中心的主任和副主任，苏珊·尚茨博士和乔迪·弗洛斯博士将 负责召开内部和外部咨询委员会会议，并定期评估 每个项目的研究进展。他们还将负责对政府的一般财政监督， 中心在尚茨博士缺席的情况下弗洛斯博士将有全权做决定。

The primary goal of this Formative Center is to assemble a multidisciplinary team of experts to address the critical gaps in our knowledge of the risks to human development from bisphenol A and phthalate exposure. We will actively involve junior investigators in this research effort, and actively communicate our research findings to the healthcare community and the public. At the heart of the research effort will be two pilot human cohort studies¿a birth cohort to be recruited in Urbana-Champaign, IL (S. Schantz, PI) and an adolescent cohort to be assessed as part of an ongoing study in New Bedford, MA (S. Korrick, PI). The Formative Center will also include laboratory animal projects (J. Juraska, PI and H. Yao, PI) which will model the timing of exposures in these human cohorts. This Administrative Core will organize and facilitate the overall program of research, including oversight, coordination and integration of all Center-related activities. This will include organizing and scheduling monthly meetings of the internal advisory committee and monthly joint lab meetings of the Center investigators, organizing yearly meetings of the Center scientists with the six-member External Advisory Committee, coordinating Community Engagement activities, and working with the Pediatric Health Specialists to translate relevant information for those in the pediatric health care community. Statistical support for the two pilot human cohort studies (Projects 1 and 2) will be provided via a subcontract to Dr. Joseph Gardiner at Michigan State University, which will be managed through the administrative core. As Director and Associate Director of the Formative Center, Drs. Susan Schantz and Jodi Flaws will be responsible for conducting Internal and External Advisory Committee meetings and regularly evaluating the research progress of each of the projects. They will also be responsible for general fiscal oversight of the Center. Dr. Flaws will have full authority to make decisions in Dr. Schantz's absence.