Training Program in Integrative Membrane Biology

描述（由申请人提供）：在综合膜生物学（TPIMB）的培训计划旨在培养生物学，生物物理学和生物膜生理学的博士前学生。现在在其第三个十年，TPIMB继续领导跨学科培训的努力，在细胞和系统生物学的接口在医学的马里兰州大学（DM SoM），通过专注于细胞膜和细胞内膜的作用，介导和整合细胞的功能和它们与环境的相互作用。该计划的指导思想是，膜生物物理学和生理学以及基于膜的信号级联的研究可以为健康和疾病状态下的细胞和组织生物学提供独特的见解。TPIMB的教师，现在有40人，资金充足，高度互动，并致力于指导学生学习与膜生物学相关的广泛学科。培训师是根据他们的兴趣、校外支持和对指导的承诺而选择的。学员的选择也是基于他们的兴趣，以及本科记录，标准化考试成绩，推荐信和以前的研究经验。学生需要采取一系列的课程，膜生物化学和生物物理学，并在膜缺陷和人类疾病之间的联系，以及在研究伦理类。他们还参加细胞和系统生理学，药理学或神经科学的入门和/或高级课程。在细胞和分子生物学，设计作为在UM SoM研究生教育的当前重组的一部分，一个新的密集的核心课程，现在也需要。学员定期参加以学生为导向的活动，如研讨会，每月聚会和年度务虚会。UM SoM通过对教师工资的贡献，为学生提供额外的津贴以及TPIMB定期活动的资金慷慨地支持该计划。目前NIH的资金支持7名受训人员，但留下许多人跟随我们的课程，并参加我们的活动没有支持。我们的研究生培训工作的增长，在最近的招聘成功，并在UM SoM的联邦资金大幅跃升表明，在资助的职位数量增加是合理的。在持续和加强的支持下，TPIMB的教师和学生可以继续带头在UM SoM整合细胞和系统生物学培训

DESCRIPTION (provided by applicant): The Training Program in Integrative Membrane Biology (TPIMB) is designed to train predoctoral students in the biology, biophysics, and physiology of biological membranes. Now in its 3rd decade, the TPIMB continues to lead the effort in interdisciplinary training at the interface of cell and systems biology at the University of Maryland School of Medicine (DM SoM), by focusing on the role of the cell membrane and intracellular membranes in mediating and integrating the functions of cells and their interactions with the environment. The program is guided by the idea that studies of membrane biophysics and physiology, and of membrane-based signaling cascades, can provide unique insights into the biology of cells and tissues, in both healthy and diseased states. The faculty of the TPIMB, now numbering 40 individuals, are well funded, highly interactive, and devoted to mentoring students studying a broad range of subjects related to Membrane Biology. Trainers are selected for their interests, extramural support, and commitment to mentoring. Trainees are also selected based on their interests, as well as undergraduate records, standardized test scores, recommendations, and previous research experience. Students are required to take a series of courses on membrane biochemistry and biophysics, and on links between membrane defects and human diseases, as well as a class in research ethics. They also take introductory and/or advanced courses in cellular and systems Physiology, Pharmacology, or Neuroscience. A new intensive core course in Cell and Molecular Biology, devised as part of the current restructuring of graduate education at UM SoM, is now also required. Trainees participate regularly in student-oriented activities, such as seminars, monthly get-togethers, and an annual retreat. The UM SoM supports this program generously through contributions to faculty salary, additional stipends for students, and funds for the TPIMB's regular activities. Current NIH funding supports 7 trainees but leaves many following our curriculum and taking part in our activities without support. The growth of our graduate training efforts, successes in recent recruitment, and the large jump in federal funding at the UM SoM suggest that an increase in the number of funded positions is justified. With continued and enhanced support, the faculty and students in the TPIMB can continue to spearhead the effort to integrate training in cell and systems biology at the UM SoM