IMAGING CORE
IMAGING CORE
批准号:
8564996
负责人:
Susan J Hagen
金额:
$30.59万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-09-01 至 2015-11-30
关键词:
AreaBasic ScienceBiologicalBiologyBostonCell physiologyCellular biologyCollaborationsComplexConfocal MicroscopyConsultDataDevelopmentDigestionDigestive System DisordersDisciplineEducationElectron MicroscopyEpithelialEpithelial CellsEquipmentEventFluorescence MicroscopyFluorescence Resonance Energy TransferFosteringGastrointestinal tract structureHospitalsHost DefenseHypersensitivityImageImage AnalysisImmune System DiseasesIndividualInstitutesInstitutionInstructionInterdisciplinary StudyIsraelLiverLocationMapsMedicalMedical centerMethodsMicroscopeMicroscopicMicroscopyMissionMucosal ImmunityNeoplasmsOpticsPancreasPediatric HospitalsPrincipal InvestigatorProductivityProtocols documentationReagentRecruitment ActivityResearchResearch PersonnelResolutionResourcesScientistServicesSolutionsStructureTechniquesTechnologyTime StudyTrainingTranslational ResearchWorkabsorptionbasegastrointestinalgastrointestinal systemimage processingimmunocytochemistryinnovationinstrumentinstrumentationinterestlight microscopymedical schoolsmeetingsmembernovelresearch and developmentsingle molecule
中文摘要
中心和核心任务介绍
哈佛消化疾病中心专注于消化道、肝脏和胰腺上皮细胞的细胞生物学和功能;以及上皮生物学如何在粘膜免疫和过敏、先天宿主防御、消化和吸收、胃肠道肿瘤的发展以及胃肠道的许多其他功能中表现出来。
该中心旨在通过提供技术资源,核心服务,科学专业知识和重要的交汇点来促进该领域的多学科研究,以促进哈佛附属医院,哈佛医学院和朗伍德医学区相邻研究机构的独立研究人员之间的密切科学和知识关系。我们还打算招聘新的和已建立的调查员到外地。
我们的首要使命是通过以下方式在消化系统疾病相关领域促进更好的基础和转化科学:连接人们,创造机会和扩展资源。
共享的智力和科学资源,以加强这一努力和我们的研究基地的生产力是由四个服务核心和行政核心(见图1-核心B)。
每个核心向HDDC提供以下一般资源:核心服务、材料和试剂、
仪器和设备“专业知识,协议和培训<$核心开发研究核心B为HDDC成员提供光学和电子显微镜,资源和科学支持,对消化系统疾病的研究至关重要。
英文摘要
Introduction to Center and Core Missions
The Harvard Digestive Disease Center is focused on the cell biology and function of epithelial cells of the alimentary tract, liver, and pancreas; and how epithelial biology manifests itself in mucosal immunity and allergy, innate host defense, digestion and absorption, the development of gastrointestinal neoplasia, and the many other functions of the Gl tract.
The Center aims to facilitate multidisciplinary research in this field by providing technical resources, core services, scientific expertise, and an important meeting point to foster close scientific and intellectual relationships among independent investigators in Harvard-affiliated hospitals, the Harvard Medical School and adjacent research institutions in the Longwood Medical Area. We also aim to recruit new and established investigators to the field.
Our overarching mission is to foster better basic and translational science in fields related to digestive diseases by: ¿connecting people, 'creating opportunity, and 'extending resources.
Shared intellectual and scientific resources to enhance this effort and the productivity of our research base are provided by four service Cores and an Administrative Core (see Figure 1-CoreB).
Each Core provides the following general resources to the HDDC: ¿ Core Services ¿ Materials and Reagents ¿
Instrumentation and Equipment "Expertise, Protocols, and Training ¿ Core-development research Core B provides HDDC members with light and electron microscopy, resources, and scientific support essential for research in the digestive diseases.
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专著(0)
科研奖励(0)
会议论文
Microscopy/Histopahology
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批准号:9442783
-
项目类别:
-
资助金额:$25.14万
-
财政年份:2017
-
负责人:Susan J Hagen
-
依托单位:
Wohlwend High Pressure Freezer for the BIDMC Electron Microscopy Core
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批准号:8825681
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项目类别:
-
资助金额:$19.94万
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财政年份:2015
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负责人:Susan J Hagen
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依托单位:
CONFOCAL MICROSCOPE: POLYCYSTIC KIDNEY DISEASE
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批准号:7334955
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项目类别:
-
资助金额:$4.27万
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财政年份:2006
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负责人:Susan J Hagen
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依托单位:
CONFOCAL MICROSCOPE: NEURODEGENERATION, ALZHEIMER'S DIS
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批准号:7334957
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项目类别:
-
资助金额:$6.41万
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财政年份:2006
-
负责人:Susan J Hagen
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依托单位:
Confocal Microscope for the BIDMC Imaging Core Facility
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批准号:7047106
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项目类别:
-
资助金额:$42.75万
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财政年份:2006
-
负责人:Susan J Hagen
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依托单位:
CONFOCAL MICROSCOPE: PROSTATE CANCER
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批准号:7334956
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项目类别:
-
资助金额:$4.27万
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财政年份:2006
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负责人:Susan J Hagen
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依托单位:
CONFOCAL MICROSCOPE: CELL BIOL, SIGNAL TRANSDUCTION, PROTEIN, CYTOPLASMIC LIPID
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批准号:7334959
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项目类别:
-
资助金额:$21.37万
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财政年份:2006
-
负责人:Susan J Hagen
-
依托单位:
CONFOCAL MICROSCOPE: SURGICAL DISEASES, WOUND HEALING
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批准号:7334958
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项目类别:
-
资助金额:$6.41万
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财政年份:2006
-
负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:6725833
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项目类别:
-
资助金额:$9.64万
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财政年份:2003
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负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:6024412
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项目类别:
-
资助金额:$2.18万
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财政年份:1999
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负责人:Susan J Hagen
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依托单位:
Microscopy and Histopathology Core B
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批准号:10378464
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项目类别:
-
资助金额:$22.87万
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财政年份:1997
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负责人:Susan J Hagen
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依托单位:
Microscopy and Histopathology Core B
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批准号:10049384
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项目类别:
-
资助金额:$24.79万
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财政年份:1997
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负责人:Susan J Hagen
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依托单位:
DAMAGE/REPAIR OF THE INTESTINAL BRUSH BORDER
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批准号:3509706
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项目类别:
-
资助金额:$10.0万
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财政年份:1991
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负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:2015959
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项目类别:
-
资助金额:$32.34万
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财政年份:1977
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负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:6137962
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项目类别:
-
资助金额:$38.47万
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财政年份:1977
-
负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:2634180
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项目类别:
-
资助金额:$33.63万
-
财政年份:1977
-
负责人:Susan J Hagen
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依托单位:
GI Mucosal Barrier in Health and Surgical Disease
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批准号:6772579
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项目类别:
-
资助金额:$34.13万
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财政年份:1977
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负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:6342426
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项目类别:
-
资助金额:$39.62万
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财政年份:1977
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负责人:Susan J Hagen
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依托单位:
GI Mucosal Barrier in Health and Surgical Disease
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批准号:6897779
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项目类别:
-
资助金额:$34.5万
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财政年份:1977
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负责人:Susan J Hagen
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依托单位:
GI MUCOSAL BARRIER IN HEALTH AND SURGICAL DISEASE
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批准号:6489626
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项目类别:
-
资助金额:$40.81万
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财政年份:1977
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负责人:Susan J Hagen
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依托单位:
海外基金