Genetic and Developmental Mechanisms of Pediatric Disease

犹他州大学儿科系建议继续其非常成功的 培训计划犹他州儿童健康研究职业发展奖（CHRCDA）计划。的 犹他州CHRCDA选择最优秀的初级教师学者进行严格的科学培训， 研究环境。犹他州CHRCDA使用经验丰富的基础-和医生-科学家作为导师， 提供专业知识，指导和实验室设施，使学者能够启动成功的职业生涯， 物理科学家犹他州CHRCDA的首要主题是遗传和发育 儿童疾病的潜在机制，为研究和发现提供了丰富的机会， to improve改善health健康for children儿童.非常有前途的学者是从毕业的研究员谁加入 系，由教师招聘或从目前的初级教师。实验室的指导经验 NIH资助的研究人员使学者能够将创新的研究方法应用于分子生物学。 遗传学和发育生物学。一个结构化的课程（由K30奖支持，以大学的 医学院）为学者提供流行病学，生物统计学，数据 管理学、医学遗传学和分子生物学。高级儿科教师提供正式的 在科学写作，授予写作和研究道德的指导。犹他州的学者们 在目前的CHRCDA方案的前四年取得的进展。前六位学者中有四位获得了K 一名学者获得了R21奖;一名学者正在重新提交一份研究报告。 K 08应用程序。这些结果表明，委托给犹他州大学和 儿科系已被有效地用于指导年轻教师的研究生涯 成员和实现CHRCDA计划的目标。

The Department of Pediatrics of the University of Utah proposes the continuation of its highly successful training program¿the Utah Child Health Research Career Development Award (CHRCDA) program. The Utah CHRCDA selects the most outstanding junior faculty scholars for rigorous scientific training in a robust research environment. The Utah CHRCDA uses experienced basic- and physician-scientists as mentors to provide the expertise, guidance, and laboratoryfacilities that enable scholars to launch successful careers as physician-scientists. The overarching theme of the Utah CHRCDA, the genetic and developmental mechanisms that underlie pediatric disease, offers rich opportunities for research and discovery that will lead to improved health for children. Highly-promising scholars are selected from graduating fellows who join the Department, by faculty recruitment or from current junior faculty. Mentored experiences in the laboratories of established, NIH-funded investigators enable scholars to apply innovative research methods to molecular genetics and developmental biology. A structured curriculum (supported by a K30 award to the University's School of Medicine) offers scholars a graduate-level didactic education in epidemiology, biostatistics, data management, medical genetics, and molecular biology. Senior pediatric faculty members provide formal instruction in scientific writing, grant writing and research ethics. Utah scholars have made exceptional progress during the first four years of the current CHRCDA program. Four of the first six scholars received K series awards; one scholar has received an R21 award; and one scholar has a pending resubmission of a K08 application. These results indicate that the resources entrusted to the University of Utah and the Department of Pediatrics have been used effectively to mentor the research careers of young faculty members and fulfill the goals of the CHRCDA program.