Developmental Research Program

Case GI癌症孢子发育研究计划（SDRP）的总体目标是开发 创新和多样化的方法，专注于GI癌症的转化研究，从病因学 通过预防筛查、诊断、治疗和生存。SPORE发展研究 该计划将提供1）财政支持，2）核心设施服务和3）知识监督和建议试点 研究项目和调查人员。重点将放在支持新的调查人员以及 用新的方法治疗胃肠道癌。为了促进转化研究，试点项目 将优先考虑2名共同主要研究者，1名基础研究者和1名临床研究者。对于有价值的建议， 个别基础或临床研究者，SDRP领导小组将确定补充翻译 调查员担任顾问。将制定特别计划以促进新领域的胃肠道癌研究 除了结肠直肠癌。案例Gl SPORE认为试点项目机制是一个重要的 启动高风险/高影响研究的机会，并将相应地提供适当的优先次序， 这样的提议。在凯斯医学院、凯斯综合癌症中心和 SPORE基金，SDRP每年将支持多达4个试点项目，每个项目50，000美元。试点项目的提供情况 将通过多个机构范围内的电子通知系统，通过与部门的直接沟通， 校长和院长，并邀请特定的科学家与令人兴奋的新方法。试点提案将 由SDRP评估小组使用NIH 9分评分系统进行评估，该评估小组由选定的一系列 参与GI癌症研究的教师和在NIH和其他国家的丰富经验 组织同侪审查研究科。

The overall objective of the Case Gl Cancer SPORE Developmental Research Program (SDRP) is to develop innovative and diverse approaches to focus on Gl Cancer translational research across the spectrum from etiology through prevention screening, diagnostics, therapeutics, and survivorship. The SPORE Developmental Research Program will provide 1) financial support, 2) Core Facility Services and 3) intellectual oversight and advice for pilot research projects and investigators. Emphasis will be placed on supporting new investigators as well as established investigators with new approaches to Gl cancers. To stimulate translational research, pilot projects with 2 Co-PI's, one basic and one clinical investigator, will be given preference. For meritorious proposals from individual basic or clinical investigators, the SDRP leadership group will identify complementary translational investigators to serve as advisors. Special plans will be instituted to stimulate Gl cancer research in new areas other than colorectal cancer. The Case Gl SPORE considers the pilot project mechanism to be an important opportunity for initiation of high risk/high impact research and will accordingly provide appropriate prioritization for such proposals. With support from the Case School of Medicine, The Case Comprehensive Cancer Center and SPORE Funds, the SDRP will support up to 4 pilot projects per year at $50,000 each. Availability of pilot projects will be announced by multiple, institution wide, electronic notice systems, by direct communication with department heads and deans and by invitations to specific scientists with exciting new approaches. Pilot proposals will be evaluated using the NIH 9 point scoring system by the SDRP Evaluation Panel composed of selected series of faculty members with involvement in Gl Cancer Research and extensive experience in NIH and other national organization peer review study sections.