Biology of Infectious Diseases Training Program

描述（由申请人提供）：建议更新是传染病生物学培训计划的延续，以培训临床和实验室为基础的传染病相关转化研究的内科科学家。该计划利用实验室和临床研究技能和广泛的教师群体解决与传染病直接相关的问题的资源。每年申请资助四名博士后学员，主要是医学博士或医学博士/博士，由UCSF传染病奖学金项目招募，也有来自研究学院实验室的博士博士后学员。我们将继续努力招募代表性不足的少数民族和妇女加入该项目。主要项目是在研究导师和职业发展委员会的密切监督下进行实践研究，该委员会是根据受训者的研究兴趣和目标选择的。研究可以在分子、细胞、整个动物、临床或种群水平上进行。已经创造了教育和培训机会，为个人在流行病学、公共卫生、全球卫生、艾滋病毒/艾滋病、基因组学、抗菌素耐药性、微生物发病机制和宿主反应以及免疫学等领域的学术医学、公共卫生或工业领域的研究和领导职位做好准备。教育计划提供特殊课程、小组会议、研究会议和研讨会、免疫学、微生物发病机制、生物统计学、流行病学、研究设计、科学写作和科学行为伦理等课程。重点放在为个别学员特别设计的个人指导和多学科互动。该计划的质量和有效性是由我们的学员在以下方面的成功来衡量的：1)完成奖学金培训，2)在同行评审期刊和研究报告上发表的论文数量和质量，3)获得研究资金（例如，独立研究奖，k奖或同等职业发展奖，r01级或同等奖项），以及4)作为医学院教师，在工业或公共卫生部门获得研究型职业。

DESCRIPTION (provided by applicant): The proposed renewal is for a continuation of the Biology of Infectious Diseases Training Program to train physician-scientists in infectious diseases-related translational research, both clinical and laboratory-based. The program draws on the laboratory and clinical research skills and resources of a broad group of faculty addressing questions directly relevant to infectious diseases. Funding is requested for four postdoctoral trainees per year, primarily MDs or MD/PhDs, recruited the UCSF Infectious Diseases Fellowship Program, but also PhD postdoctoral trainees from research faculty laboratories. We continue to improve our efforts to recruit underrepresented minorities and women into the program. The main program is a hands-on research experience under the close supervision of a research mentor and a career development committee selected on the basis of the research interests and goals of the trainee. Research may be at the molecular, cellular, whole animal, clinical, or population levels. Educational and training opportunities have been created to prepare individuals for research and leadership positions in academic medicine, public health, or industry in the areas of epidemiology, public health, global health, HIV/AIDS, genomics, antimicrobial resistance, microbial pathogenesis and host response, and immunology. The educational program provides for special courses, small group conferences, research conferences and seminars, coursework in immunology, microbial pathogenesis, biostatistics, epidemiology, study design, scientific writing, and ethics of scientific conduct. Emphasis is placed on personal instruction specifically designed for individual trainees and on multidiscipline interactions. The quality and effectiveness of the program is measured by the success of our trainees in 1) completion of fellowship training, 2) the number and quality of publications in peer-reviewed journals and research presentations, 3) obtaining research funding (e.g., independent research awards, K-awards or equivalent career-development awards, R01-level or equivalent awards), and 4) attainment of a research-oriented career as medical school faculty, in industry, or in the public health sector. PUBLIC HEALTH RELEVANCE: Infectious diseases are the third most common cause of death in the United States, despite availability of antibiotics, vaccines, and high standards of public health and the leading cause of death worldwide. Our program supports the training of young scientists that will address high impact research questions aimed at improving our knowledge, treatment, control, and prevention of infectious diseases.