Research Core

少数民族青年和成年人健康和风险中心(CHAME)致力于少数民族社区的慢性病预防，重点是年轻人和年轻人。Charge汇集了来自加州大学旧金山分校(UCSF)、旧金山综合医院(SFGH-一家为旧金山不同人群提供医疗保健的首屈一指的安全网机构)、旧金山州立大学(SF State University)(一家少数族裔服务机构，有大量拉丁裔学生)的研究人员。加州北部Kaiser Permanente研究部、加州大学伯克利分校和斯坦福大学以及社区合作伙伴。这种方法显然是跨学科的，将具有医学、儿科学、家庭医学和妇产科临床专业知识的研究人员与那些在差异研究、遗传学、流行病学、生物统计学、定性方法、公共卫生、传播学和健康心理学方面具有方法论专业知识的研究人员联系起来。 这3个魅力研究分项目的共同规划目标是了解青年和成年后采取的行为以及这一年龄段存在的其他风险因素对种族/少数民族人口慢性病的影响。了解生物、行为、社会、文化和环境因素在慢性病风险中的作用，并对这些潜在因素采取行动 各机制对改善少数群体健康并最终消除健康差距抱有最大希望。研究核心的主要作用是协调和支持所有3个拟议的次级项目，以实现这一总体目标。此外，研究核心与培训和参与社区健康外展(ECHO)核心进行沟通，以实现魅力的总体目标。3个子项目中每个项目的目标 而魅力的总体目标将通过驻留在这个核心中的领导力、专业知识、沟通功能、方法支持和建模来高效和有效地服务。 研究核心有以下主要目的和目标： 研究核心目标1。协调三个子项目中每一个项目的方法支持，以优化设计、数据系统和分析方法。 研究核心目标2.将来自新开发的OurSpace邻居数据库的空间数据与来自Charge研究子项目的个人级别数据相结合： (A)绘制旧金山的差异地图，以及促成这些差异的行为和资源的分布/可获得性，以供魅力培训和回声核心使用；(B)提供区域一级的数据，供3个研究分项目中的2个项目进行分析。 研究核心目标3.综合3个魅力分项目的结果，以开发模型，以揭示青春期和青壮年可能发生的事件对未来生活差异的影响。这些模式将有助于传播次级项目的成果，特别是通过ECHO核心传播，并将包括： (A)一个复杂的系统模型，以说明青春期和青壮年差异的决定因素之间的关系，以及 (B)扩展现有模式，以了解加州关于差异决定因素的干预措施所涉政策问题。 研究核心将由罗伯特·A·希亚特执导。医学博士。世卫组织是加州大学旧金山分校流行病学和生物统计学教授和主席，具有领导力、流行病学、监测和差异研究方面的专业知识。 其他关键人员包括David Rehkopf博士。SCD。时速。拥有先进流行病学方法和统计建模方面的专业知识，以及Bibbins-Domingo博士。博士、医学博士和医学硕士，是魅力的整体PI，在临床医学、流行病学和慢性病干预建模方面拥有专业知识。

he Center for Health And Risk in Minority youth and adults (CHARM) is dedicated to chronic disease prevention in minority communities, with a focus on youth and young adults. CHARM brings together investigators from the University of California, San Francisco (UCSF), SF General Hospital (SFGH - a premier safety net institution providing healthcare to the diverse population of SF), SF State University (a minority serving institution with a large Latino student body). Northern California Kaiser Permanente Division of Research, UC Berkeley, and Stanford University, as well as community partners. The approach is explicitly transdisciplinary, linking investigators with clinical expertise in medicine, pediatrics, family medicine, and obstetrics and gynecology with those with methodological expertise in disparities research, genetics, epidemiology, biostatistics, qualitative methods, public health, communication sciences, and health psychology. The 3 CHARM research sub-projects share the programmatic goal of understanding the influence that behaviors adopted in youth and young adulthood and other risk factors presence during this age period exert as precursors to chronic disease in racial/ethnic minority populations. Understanding the role of biological, behavioral, social, cultural, and environmental factors in chronic disease risk and acting on these underlying mechanisms holds the best hope for improving minority health and ultimately eliminating health disparities. The primary role of the Research Core is to coordinate and support all 3 proposed sub-projects in achieving this overall goal. Additionally, the Research Core communicates with the Training and Engaging Community forHealth Outreach (ECHO) cores to achieve the overall goals of CHARM. The Aims of each of the 3 sub-projects and the overall goal of CHARM will be efficiently and effectively served by the leadership, expertise, communication functions, methods support, and modeling that will reside in this Core. The Research Core has the following primary aims and objectives: Research Core Aim 1. To coordinate methodological support utWlzed in each of the 3 sub-projects to optimize design, data systems, and analytic methods. Research Core Aim 2. To combine spatial data from a newly developed OurSpace Neighborhood Database with individual-level data from CHARM research sub-projects: (a) to map disparities in San Francisco, as well as behaviors and distribution/availability of resources that contribute to these disparities for use by the CHARM Training and ECHO cores, and (b) to provide area-level data for analyses within 2 of the 3 research sub-projects. Research Core Aim 3. To synthesize results of the 3 CHARM sub-projects in order to develop models that will inform the likely impact events in adolescence and young adulthood have on disparities in later life. These models will aid in the dissemination of the results of the sub-projects, particularly by the ECHO Core, and will include: (a) a complex systems model to illustrate the relationships of the determinants of disparities in adolescence and young adulthood, and (b) an extension of an existing model for understanding the policy implications oi interventions on determinants of disparities in California. The Research Core will be directed by Robert A. Hiatt. MD, PhD. Who is Professor and Chair of Epidemiology & Biostatistics at UCSF with expertise in leadership, epidemiology, surveillance, and disparities research. Other key personnel include Dr. David Rehkopf. ScD. MPH. with expertise in advanced epidemiologic methods and statistical modeling, and Dr. Bibbins-Domingo. PhD, MD, MAS who is overall PI of CHARM and who has expertise in clinical medicine, epidemiology, and chronic disease intervention modeling.