Executive Team & Coordinating Core (Page 273)

执行团队和协调核心的主要目标是确保综合、一致和 HNRC的有效科学操作。高管团队(ET)。由中心主任组成， 联席董事、副董事和中心经理。ET提供日常领导 HNRC。ET从科学咨询委员会(年度独立咨询委员会)获得建议和反馈 对国家核研究中心科学和方案进展的评价)，参与咨询委员会(反馈意见 和社区咨询委员会(社区提供者的反馈)，作为 以及内部调查委员会(制定政策和审查科学进展)。这个 协调核心执行ET设置的优先级，并提供多项目所必需的服务 中心。控制中心由四个单元组成：管理单元负责组织中心的分配 资源，协调中心的各种活动，组织对中心和核心的年度评估， 促进向科学界和普通社区传播信息，并确保HNRC 活动完全符合所有大学、州和联邦政策。数据管理和 信息系统股(DMIS)处理所有与中心相关的数据，并确保与 通过可上网的数据资源系统执行外部项目，支持国际努力； 维护内部和外部信息传播的网站。统计股提供 在项目开发、实施和公布调查结果的所有阶段提供统计服务。 参与者应计和留存(PAR)股招募新的感兴趣的队列(例如，早期感染 病例、老年艾滋病毒+成人)，维持信息丰富的纵向队列，管理潜在研究花名册 参与者(根据具体学习需要招募他们)，并提供咨询服务。DMIS， 统计和分析股也参与方法的制定。几个工作组提供协助和指导 核心，包括研究审查委员会(审查中心资源的申请并提供 讨论拟议研究/手稿的论坛)；人类主题委员会(监测人类 主题和IRB问题，特别是保密问题)。通过这些过程和结构，ET和 协调核心确保一个真正的多学科研究中心的运行，并提供中央 协调和领导国际研究和培训工作。

The primary aim of the Executive Team and Coordinating Core is to ensure integrated, coherent, and effective scientific operations at the HNRC. The Executive Team (ET). is comprised of the Center Director, Co-Director, Associate Directors, and Center Manager. The ET provides day-to-day leadership of the HNRC. The ET receives advice and feedback from the Scientific Advisory Board (annual independent evaluation of HNRC scientific and programmatic progress), the Participant Advisory Board (feedback from participants to the Director), and the Community Advisory Board (feedback from community providers), as well as internally from the Council of Investigators (sets policy and reviews scientific progress). The Coordinating Core implements the priorities set by the ET and provides services essential to a multiproject Center. The CC is comprised of four Units: The Administrative Unit organizes the distribution of center resources, coordinates various Center activities, organizes annual evaluations of the Center and Cores, facilitates information dissemination to the scientific and general communities, and ensures that HNRC activities are fully compliant with all university, state, and federal policies. The Data Management and Information Systems Unit (DMIS) processes all Center-related data and ensures seamless interaction with external projects via an Internet-accessible data resource system, supports international efforts, and maintains the web site for internal and external information dissemination. The Statistics Unit provides statistical services during all phases of project development, implementation, and publication of findings. The Participant Accrual and Retention (PAR) Unit recruits new cohorts of interest (e.g., early infection cases, older HIV+ adults), maintains an informative longitudinal cohort, manages a roster of potential study participants (recruiting them as required for specific studies), and provides consulting services. The DMIS, Statistics, and PAR Units also engage in methods development. Several working groups assist and guide the Core, including the Research Review Committee (reviews requests for Center resources and provides a forum to discuss proposed studies/manuscripts); the Human Subjects Committee (monitors Human Subjects and IRB issues, especially confidentiality). Through these processes and structures, the ET and Coordinating Core assure the operation of a truly multidisciplinary research center and provide central coordination and leadership for international research and training efforts.