COBRE: LSU: COMPUTATIONAL NEUROSCIENCE CORE FACILITY

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 单个细胞内的复杂生物系统由复杂的耦合非线性动力学过程控制。这种系统以非直观的方式对扰动作出反应，并且可以通过将信号系统的连贯描述合成为一组可以数值求解的耦合非线性常微分方程来最好地理解。这样的系统可以用于协同设计实验，以确认和扩展我们对生物学的理论理解。这个核心模块由一个专用服务器组成，COBRE参与者可以访问该服务器，用于计算机建模，以帮助他们更好地预测实验结果。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Complex biological systems within a single cell are governed by complex coupled nonlinear dynamical processes. Such systems respon to perturbations in nonintuitive ways and can be best understood by synthesizing a coherent description of the signaling system as a set of coupled nonlinear ordinary differential equations that can be solved numerically. Such a system can be used to synergistically design experiments to confirm and extend our theoretical understanding of the biology. This core module consists of a dedicated server that can accessed by COBRE participants for use in computer modeling to help them better predict the results of there experiments.