CALCIUM DYNAMICS IN DIFFERENTIATED NEUROBLASTOMA CELLS

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 细胞内钙动力学是细胞外刺激转导的一条普遍存在的信号通路。我们之前已经完成了一项关于神经细胞中钙动力学的联合实验和建模研究，该研究继续作为虚拟细胞软件系统支持的理论和建模交互的标准。该系统为我们研究浦肯野细胞钙动力学(SPID0010)提供了一个方便的模型。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Intracellular calcium dynamics is a ubiquitous signaling pathway for the transduction of extracellular stimuli. We had previously completed a combined experimental and modeling study on calcium dynamics in a neuronal cell that continues to serve as a standard for the interaction of theory and modeling that is enabled by the Virtual Cell software system. This system now serves as a convenient model for our studies of Purkinje cell calcium dynamics (SPID0010).