Tufts Clinical and Translational Research Institute

项目总监/首席调查员(最后，第一。中)：Selker，Harry P. 项目摘要(请参阅实例)： 申请我们的第二个CTSA，塔夫茨临床和翻译科学研究所(CTSL)仍然热衷于 致力于全方位的临床和转化性研究(CTR)，以实现 生物医学，不仅仅是板凳到床边(T L)的翻译，对健康至关重要的影响，翻译 纳入有效的临床实践(“T2”)、提供护理和公共卫生(“T3”)和卫生政策(“T4”)。 我们在以前的CTR资源、服务和教育项目的基础上启动了Tuft CTSL，我们特意 选定的合作伙伴将利用并补充彼此的特殊资产。我们的38个战略- 选定的合作伙伴包括12家塔夫茨大学学校/研究中心、10家塔夫茨医院、3家学术机构 机构(布兰迪斯大学、东北大学、兰德公司)，八个社区 组织和五个行业合作伙伴，突出和协同的资源、机会和 跨T1-T4专业的教育。在我们的应用程序的四个部分中描述了四个基于 本平台：目标1：通过以下方式全面加强塔夫茨CTSL：1)组织和领导其合作伙伴 致力于CTR的这一共享之家；2)将所有合作伙伴的高效访问扩展到全方位 以促进跨学科和跨机构协作CTR的方式提供高质量资源；3) 通过地方和国家的领导和开发新的方法推动CTR领域的发展；4) 在T1-4专业范围内提供创新和有针对性的教育和培训。(第一节)目标2： 运作和实施CTR总部及其基础设施、服务和方案，包括ITS 中央办公室人事、行政和财务管理系统、委员会和其他 必要的结构。(第二节)目标3：维持和发展创新资源、服务和政策， 支持和促进协作、跨学科、全方位的翻译研究。(第三节)AIM 4：通过T1-T4级的教育和培训，发展和扩大CTR工作人员队伍， 特别关注解决从长凳到床边以及从床边到大范围的翻译差距 对健康的影响。(第IV节) 相关性(请参阅说明)： 塔夫茨临床和翻译科学研究所使用临床和翻译的整个光谱 帮助实现生物医学科学的承诺和公众需求的研究(CTR)。这包括BASE 到床边(？T1“)翻译，关键是对健康有影响，翻译成有效的临床实践 (“T2”)、“保健提供和公共卫生”(“TS”)和卫生政策(‘74“)。

Program Director/Principal Investigator (Last, First. Middle): Selker, Harry P. PROJECT SUMMARY (See Instnjctions): Applying for our second CTSA, Tufts Clinical and Translational Science Institute (CTSl) remains avidly committed to involving the full spectrum of clinical arid translational research (CTR) to meet the promise of biomedical science, not only bench to bedside ( T l " ) translation, crucial to having health impact, translation into effective clinical practice ("T2"), care delivery and public health ("T3"), and health policy ('T4"). In 2008 we started Tufts CTSl building on prior CTR resources, services, and educational programs, we purposely selected partners that would leverage and complement each other's special assets. Our 38 strategically- chosen partners include 12 Tufts University schools/research centers, ten Tufts hospitals, three academic Institutions (Brandeis University, Northeastern University, RAND Corporation), eight community-based organizations, and five industry partners, an outstanding and synergistic resources, opportunities, and education across the T1-T4 spectnjm. Described in our application's four sections are four alms that build on this platform: AIM 1: Strengthen Tufts CTSl overall by: 1) organizing and leading its partners in their commitment to this shared home for CTR; 2) expanding efficient access for all partners to a full spectrum of high-quality resources in a way that promotes collaborative CTR across disciplines and institutions;3) advancing the field of CTR through local and national leadership and development of novel methods;4) providing innovative and targeted education and training across the T1-4 spectmm. (Section I) AIM 2: Operationalize and implement the CTR home and its infra- stnjcture, services and programs, including its central office personnel, administrative and financial management systems, committees, and other necessary structures. (Section II) AIM 3: Sustain and grow innovative resources, services, and policies that support and promote collaborative, cross-disciplinary, full-spectrum translational research. (Section III) AIM 4:Develop and broaden the CTR workforce through education and training across the T1-T4 spectrum, with a specific focus on addressing translational gaps between bench to bedside and from bedside to widespread impact on health. (Section IV) RELEVANCE (See Instructions): Tufts Clinical and Translational Science Institute uses the entire spectrum of clinical and translational research (CTR) to help meet the promise and the public's needs of biomedical science.This includes bench to bedside (¿T1") translation and crucially for having health impact, translation into effective cllnicalpractlce ("T2"), care delivery and public health ("TS"), and health policy ('74").