Core Center for Sensory Mechanisms

描述（由申请人提供）：这是P30 DC005211“感觉机制研究核心”的竞争性续期申请，为一组NIDCD资助的实验室提供共享服务。该提案包括一个行政外壳，工程和组织学核心。这些研究核心将使人们能够更有效地利用共同服务，并获得专门知识。工程核心包括一名高级程序员和电子技术员、中央数据服务器、听觉表型分析设施、先进的声学刺激和分析设计以及一台大幅面海报打印机。组织学核心提供标准光学显微镜和免疫荧光组织制备方面的支持和培训。此外，组织学核心支持高级EM显微镜，超微切片和EM访问，以及训练有素的组织学家指导共聚焦成像。组织学核心将在共用设施中纳入共聚焦显微镜。工程学和组织学核心通过行政外壳组织起来，进一步加强了听力和平衡中心，现在是感觉生物学中心，其中包括NIDCD资助的约翰霍普金斯研究化学感觉的实验室。

DESCRIPTION (provided by applicant): This is the application for competing renewal of P30 DC005211, "Sensory Mechanisms Research Core" to provide shared services to a group of NIDCD-funded laboratories. The proposal includes an Administrative Shell, Engineering and Histology Cores. These Research Cores will enable more efficient utilization of common services, as well as access to specialized expertise. The Engineering Core includes a senior programmer and electronics technician, central data servers, auditory phenotyping facility, design of advanced acoustic stimuli and analyses, and a large-format poster printer. The Histology Core offers support and training in tissue preparation for standard light microscopy and immunofluorescence. In addition the Histology Core supports a senior EM microscopist, ultramicrotomy and EM access, as well as trained histologists to guide confocal imaging. The Histology Core will incorporate a confocal microscope into the shared facilities. Together the Engineering and Histology Cores, organized through the Administrative Shell, further strengthen the Center for Hearing and Balance, and now the Center for Sensory Biology which includes NIDCD-funded laboratories studying chemical senses at Johns Hopkins.