Institutional Training Grant in Pediatric Gastroenterology

此申请是第一次更新的机构培训计划（T32）在儿科 科罗拉多丹佛大学胃肠病学、肝病学和营养学和儿童医院 位于科罗拉多奥罗拉安舒茨医学院的医院。该计划的总体目标是 为不同的博士后学员提供一个特殊的监督培训经验 使他们能够发展或提高他们的研究技能和知识，为 儿科胃肠病学或肝病学相关研究职业。其基本原理是 该计划是利用新的安舒茨医疗提供的新的物理和科学的协同作用， 校园，一个杰出的承诺经验丰富的研究教师，和一个潜在的申请人的大池。 提供两种研究培训途径，以培养基础实验室科学家或临床- 翻译科学家研究培训将集中在五个科学主题：发病机制和 儿科肝病的治疗，儿科肠道疾病的免疫发病机制，粘膜 免疫生物学、儿童肥胖和代谢综合征以及健康结果研究。T32教师 由25名个人组成，他们在R 01，U 01或计划项目赠款中获得了超过2700万美元的资金， 非常成功的训练记录。基础研究经验通过研究生课程、研讨会 多学科会议。临床转化研究的实习生将参加硕士课程 临床科学研究生课程学位，并将利用科罗拉多的基础设施 临床和转化科学研究所。该研究培训计划旨在为2-3年 计划，一般开始在2”"* 年的亚专业奖学金或以下完成博士学位或 相当于合格的候选人主要来自国家认可的儿科奖学金 胃肠病学，具有其他学科候选人的潜力，包括消化病学，营养学和 相关基础科学领域。培训生提供至少80%的保护时间为2或3年， 在有指导和结构化的环境中进行培训。教育和研究经验的质量 将由学员、导师和执行委员会根据规定的指标密切监测， 持续改进过程。在过去3年完成T32培训的7名学员中， 5有全职的学术职位，并在发展自己的研究生涯非常早。继续 要求增加4个培训职位，并在第2年增加5个职位，以便进行3年的培训。 相关性（参见说明）： 这个T32培训计划通过培训下一代医生和博士学位与儿童健康相关 科学家们通过科学发现将促进对GI，肝病和 营养失调本培训计划中对研究培训的投资将为 让学员成为未来的领导者，教师和导师，帮助指导Gl的方向， 肝脏学和营养学。

This application is for the first renewal of the Institutional Training Program (T32) in Pediatric Gastroenterology, Hepatology and Nutrition at the University of Colorado Denver and The Children's Hospital at the Anschutz's Medical Campus in Aurora, Colorado. The overall goal of this program is to provide a diverse group of post-doctoral trainees with an exceptional supervised training experience to allow them to develop or enhance their research skills and knowledge in preparation for a pediatric gastroenterology or hepatology related research career. The underlying rationale for this program is to take advantage of new physical and scientific synergies provided by the new Anschutz Medical Campus, an outstanding committed experienced research faculty, and a large pool of potential applicants. Two pathways of research training are offered to produce Basic Laboratory Scientists or Clinical- Translational Scientists. Research training will be focused in five scientific themes: pathogenesis and treatment of pediatric liver disease, immunopathogenesis of pediatric intestinal disease, mucosal immunobiology, pediatric obesity and metabolic syndrome and health outcomes research. The T32 faculty comprises 25 individuals with over $27 million dollars in R01, U01 or program project grant funding and a highly successful training record. Basic research experiences are augmented by graduate courses, seminars and multidisciplinary meetings. Trainees in clinical-translational research will participate in the Masters Degree in the Clinical Sciences Graduate Program and will leverage the infrastructure of the Colorado Clinical and Translational Sciences Institute. The research training program is designed to be a 2-3 year program, generally beginning in the 2""* year of subspecialty fellowship or following completion of a PhD or equivalent. Eligible candidates are primarily drawn from the nationally recognized fellowship in Pediatric Gastroenterology, with the potential for candidates in other disciplines including neonatology, nutrition and related basic science fields. Trainees are provided a minimum of 80% protected time for 2 or 3 years of training in a mentored and structured environment. The quality of the educational and research experiences will be closely monitored by the trainees, mentors and Executive Committee with defined metrics and ongoing improvement processes. Of the 7 trainees who have completed the T32 training in the past 3 years, 5 have full-time academic positions and are very early in developing their research careers. The continuation of 4 training positions is requested with the addition of a 5"^ position in year 2 to allow for 3 years of training. RELEVANCE (See instructions): This T32 Training Program is relevant to child health by training the next generation of physician and PhD scientists who through scientific discovery will advance the care of children with Gl, hepatology and nutritional disorders. The investment in research training in this Training Program will provide a foundation for the trainees to become the future leaders, teachers and mentors who will help guide the direction of Gl, hepatology and nutrition in the future.