Graduate Training Program in Cancer Biology - Renewal 01

程序摘要 芝加哥大学的癌症生物学培训项目(CBTP)是一个多学科的项目 该项目的核心任务是培养不同领域的研究生和博士后研究人员 癌症研究领域，包括但不限于癌症生物学的基本分子机制， 系统方法、发育程序的重新启动和模式生物的使用、器官部位生物学、 癌症治疗学和癌症群体遗传学。此外，我们的受训人员在 假设的建立和检验、科学努力的伦理、教学技能和对如何 他们的工作为人类福祉和社会疾病管理做出了贡献。 在过去5年的培训资助中，我们的癌症生物学项目已经站稳了脚跟。 作为一个有效和充满活力的培训计划，培训下一代癌症生物学家需要满足 社会上癌症发病率的增加带来了医疗保健方面的挑战。我们的43名教员培训师 保持着杰出的出版记录，并获得了许多享有盛誉的荣誉。尽管 在一个充满挑战的资助环境下，我们的教职员工在2013年增加了对他们研究的直接资助 2008年。强大的机构支持也使我们能够招聘有才华的新教师，他们的专业知识 增加了我们的学员在令人兴奋的癌症生物学和科学新领域的研究机会。 值得注意的是，我们继续收到越来越多的合格申请者参加我们的计划。我们是 还感到高兴的是，我们能够大幅增加代表性不足的少数群体的数量 这些实习生是我们最具活力的学员之一。 在过去的5年里，我们对我们的课程进行了严格的评估，以进一步改进我们的课程。 以迎接这十年来癌症研究面貌的变化。特别是，我们开发了新的方面 课程，改变了对正式课程的要求，以及引入了个人进步 为学员提供发展机会。该项目还在凯博士的新领导下 麦克劳德接替Geof Greene博士担任这项培训拨款的主任。与以往的所有领导层一样 由于麦克劳德博士与格林博士在 在过去的5年里，格林博士仍然是领导结构的一部分。重要的是，麦克劳德博士带来了 更新精力和想法，使该计划在其培训目标中保持有目的和目标导向。 总而言之，我们拥有由教员培训师组成的专家机构和一群才华横溢的年轻实习生，外加一个 不断改善课程和培训环境，我们的计划在以下方面取得了很大成功 实习生的工作效率和职业成就。鉴于我们计划的这些优势和我们持续的能力 招聘更多合格、优秀的实习生，我们建议该计划的需要和优点 在此次培训拨款续签中保留博士后(8名)和博士后(3名)的名额。

PROGRAM ABSTRACT The Cancer Biology Training Program (CBTP) at the University of Chicago is a multi-disciplinary program whose core mission is to train graduate students and post-doctoral researchers in different areas of cancer research, including but not limited to fundamental molecular mechanisms in cancer biology, systems approaches, reactivation of developmental programs and use of model organisms, organ site biology, cancer therapeutics and cancer population genetics. In addition, our trainees receive robust grounding in hypothesis building and testing, the ethics of scientific endeavor, teaching skills and an understanding of how their work contributes to human well-being and disease management in society. Over the past 5 years of training grant support, our cancer biology program has firmly established itself as an effective and vibrant training program, training the next generation of cancer biologists needed to meet the health cares challenges arising from increasing cancer incidence in society. Our 43 faculty trainers have maintained an outstanding publication record and have been recognized by many prestigious honors. Despite a challenging funding climate, our faculty have increased direct funding of their research in 2013 compared to 2008. Strong institutional support has also allowed us to recruit talented new faculty whose expertise has increased the research opportunities for our trainees in exciting new areas of cancer biology and science. Significantly, we continue to receive an ever-increasing number of qualified applicants to our program. We are also pleased that we have been able to make significant increases in numbers of under-represented minorities recruited to our program, and these trainees are amongst our most dynamic. We have evaluated our program rigorously over the past 5 years to improve yet further our curriculum to meet the changing face of cancer research in this decade. In particular, we have developed new aspects of the curriculum, with altered demands in formal coursework, as well as introduced advances in personal development opportunities for trainees. The program has also come under new leadership with Dr. Kay Macleod taking over from Dr. Geof Greene as Director of this training grant. As with all previous leadership changes to the program, continuity remains thanks to Dr. Macleod having worked closely with Dr. Greene in the past 5 years and Dr. Greene remaining part of the leadership structure. Importantly, Dr. Macleod brings renewed energy and ideas to keep the program purposeful and goal-oriented in its training objectives. In summary, with our expert body of faculty trainers and talented group of young trainees, plus a constantly improving curriculum and training environment, our program has been highly successful in terms of trainee productivity and career outcomes. Given these strength of our program and our sustained ability to recruit increased numbers of qualified, outstanding trainees, we suggest that the program needs and merits retaining the number of pre-doctoral (8) and post-doctoral (3) slots in this training grant renewal.