Musculoskeletal Quantitative Imaging and Image Processing Research Core

肌肉骨骼成像和图像处理研究(MQIR)核心的目标是提供 为临床前(组织样本和)定制图像采集、重建和定量分析 动物模型)，以及人类肌肉骨骼疾病的定量成像。MQIR核心具有 以下目标是其对CCMBM总体使命的贡献的一部分。具体目标I：提供定量磁共振成像序列，计算机断层扫描(CT) 以及临床前和人体肌肉骨骼组织的正电子发射断层扫描(PET)方法。具体目标二：开发新的图像分级和定量分析：提供模板、培训、 并对放射照片、CT和MR图像、软件包的临床分级实施可靠的措施 用于图像的后处理、可视化和定量分析。具体目标三：提供成像数据的解释，并评估与生化、组织学和 生物力学测量。开发和维护记录参数的拟议项目的数据库 从单一的和系列的成像检查以及相关的临床或实验检查中提取的 终端。具体目标四：我们将提供一个门户网站，这是以前使用成像技术进行研究的例子 临床和研究影像服务的端点和详细描述将在Web上呈现 传送门。工作人员将审查新用户对研究协作和服务的在线请求， 在研究的基础上，将与适当的个人进行初步磋商。后处理和 将提供成像信息学，以帮助研究人员设计研究并申请他们的试点和 可行性拨款。具体目标五：我们还将积极开展外联活动，吸引潜在的新用户，参加CCMBM研讨会活动，提供成像研讨会和工作坊，介绍新的成像、图像处理、 给核心社区。

The goal of the Musculoskeletal Imaging and Image Processing Research (MQIR) Core is to provide customized image acquisition, reconstruction and quantitative analysis for pre-clinical (tissue samples and animal models), and human quantitative imaging in musculoskeletal diseases.The MQIR Core has the following aims as part of its contribution to the overall mission of the CCMBM. Specific Aim I: To provide quantitative magnetic resonance imaging sequences, computed tomography (CT) and positron emission tomography (PET) methods for pre-clinical and human musculoskeletal tissues. Specific Aim II: To develop novel image grading and quantitative analysis: To provide templates, training, and implement robust measures for clinical grading of radiographs, CT and MR images, software packages for post-processing, visualization and quantitative analysis of images. Specific Aim III: To provide interpretation of imaging data and assess links to biochemical, histological, and biomechanical measures. Develop and maintain databases for proposed projects that record parameters that are extracted from single and serial imaging examinations and the relevant clinical or experimental endpoints. Specific Aim IV: We will provide a web portal, examples of previous studies that have used imaging endpoints and detailed descriptions of clinical and research imaging services will be represented on the web portal. On-line requests from new users for research collaboration and service will be reviewed by the staff, and based on the studies, initial consultation with appropriate individuals will be set up. Post-processing and imaging informatics will be provided to assist researchers design studies and apply for their Pilot and Feasibility grants. Specific Aim V: We will also perform proactive outreach to attract potential new users, participate in CCMBM seminar activities to provide imaging seminars and workshops to introduce new imaging, image processing, to the Core community.