Genomics Core Facility

UNMC DNA微阵列和测序核心设施的目标是提供最先进的遗传学 为区域学术研究界提供研究服务。该核心将促进正在进行的 神经感觉系统COBRE的分子生物学的使命，继续提供功能 COBRE研究人员开展研究项目所需的基因组学基础设施。DNA 微阵列和下一代DNA测序是必不可少的研究工具，使研究人员能够 确定有助于正常和疾病相关发育的潜在生物学机制， physiology.它们是有助于促进开发新的生物技术的最终研究目标的关键组成部分。 治疗模式，以帮助患者的生物医学问题。这些技术需要专门的 设备和技术专长，因此在核心环境中表现最好， 专门为访问服务的其他研究人员开发分析和执行实验。的 核心为研究人员提供各种服务，包括DNA微阵列以及传统和下一代 第二代DNA测序。为了最大限度地发挥最先进的基因组学技术的效益， 核心主任、工作人员和研究人员之间的持续互动是必要的， 核心致力于此。此外，基因组学技术在以下领域正在经历快速增长： 研究应用，因此，核心将根据需要不断开发和实施新技术 并努力获得和/或升级必要的仪器。为确保长期可持续性， 对核心而言，是确保它继续以具有成本效益和及时的方式提供服务。的 该核心的总体使命是为研究人员提供基本服务， 研究人员在使用这些技术，并保持目前的仪器和 技术程序，以帮助促进有利于病人健康的长期目标。

The goal of the UNMC DNA Microarray and Sequencing Core facility is to provide state-of-the art genetic research services to the regional academic research community. The core will contribute to the ongoing mission of the Molecular Biology of Neurosensory Systems COBRE by continuing to provide the functional genomics infrastructure necessary for COBRE researchers to conduct their research projects. DNA microarrays and next generation DNA sequencing are essential research tools that enable researchers to identify underlying biological mechanisms contributing to both normal and disease related development and physiology. They are critical components that help to facilitate the ultimate research goals of developing new treatment modalities to help patients with biomedical problems.These technologies require specialized equipment and technological expertise and as such are best performed in a core setting where the focus is specifically to develop assays and perform experiments for other researchers accessing the services. The core offers a variety of services to researchers including DNA Microarray as well as traditional and next generation DNA sequencing. In order to maximize the benefit of state-of-the art genomics technologies, it is imperative that a continual interaction between the core director, staff, and researchers is ongoing and the core is committed to this. In addition, genomics technology is undergoing rapid growth in the area of research applications, therefore the core will continually develop and implement new technologies as needed and work to obtain and/or upgrade necessary instrumentation. To ensure long-term sustainability, the vision for the core is to ensure that it continues to provide the services in a cost-efficient and timely fashion. The overall mission of this core is to provide essential services to researchers, communicate and train investigators in the use of these technologies, and stay current with respect to instrumentation and technological procedures, in order to help facilitate the long term goal of benefiting the health of patients.