Womens HIV Risk: Alcohol Intoxication and Sexual Victimization History

描述(由申请人提供)：拟议的项目是R01AA016281的竞争性更新，并将继续进行一项研究计划，调查年轻成年女性酒精消费、性受害历史和性传播感染/艾滋病毒相关风险承担之间的关系。最初的项目通过两个饮酒实验，调查了女性酒精中毒、性受害史和伴侣特征对女性HIV相关性行为决策的影响。现有的研究和最初项目的发现都表明，情绪和情绪调节结构可能在以下两个方面提供了关键的解释联系：1)性受害和更多的性风险，2)饮酒和更多的性风险。然而，由于现有的大部分研究都是描述性的和相互关联的，人们对情绪和情绪调节结构如何在瞬间影响女性的性决策过程知之甚少。此外，关于这些情感因素如何调节或缓和酒精和性受害历史对高风险性行为决定的影响，人们更是知之甚少。本项目通过两种方法解决这一知识差距：每天30天的日记评估和以实验室为基础的酒精摄入实验。在完成筛查程序和在线基线调查后，年龄在21-30岁之间的女性(n=600)将完成30天的每日情绪状态、情绪调节策略以及饮酒和性行为风险行为的日记评估，以评估情绪状态、情绪调节、饮酒和危险性行为之间的日常关系。在每天的日记阶段结束后，相同的参与者将完成一项实验室实验，评估酒精中毒和情绪环境对危险的性行为意图的即时影响。广义估计方程将被用来检验情绪状态和情绪调节策略对酒精消费和性行为风险行为的日常影响。结构方程建模和其他基于回归的分析将被用来检验酒精中毒和实验操纵的情绪环境对性风险意图的实验影响。

DESCRIPTION (provided by applicant): The proposed project is a competing renewal of R01AA016281 and will continue a program of research investigating the relationships among alcohol consumption, sexual victimization history, and STI/HIV-related risk taking in young adult women. The original project investigated the influence of women's alcohol intoxication, sexual victimization history, and partner characteristics on women's HIV-related sexual decision making through two alcohol administration experiments. Both extant research and findings from the original project suggest that emotions and emotion regulation constructs may provide a key explanatory linkage between: 1) sexual victimization and increased sexual risk taking and 2) alcohol consumption and increased sexual risk taking. However, because the bulk of the extant research has been descriptive and correlational, little is known about how emotions and emotion regulation constructs operate in-the-moment to influence women's sexual decision-making processes. Moreover, even less is known about how these emotional factors may mediate or moderate the effects of alcohol and sexual victimization history on risky sexual decisions. The present project addresses this knowledge gap through two methods: a 30 day daily diary assessment and a laboratory-based alcohol administration experiment. After completing a screening procedure and an online baseline survey, women aged 21-30 of elevated sexual risk (n = 600) will complete a 30 day daily diary assessment of their emotional states, emotion regulation strategies, and their drinking and sexual risk behaviors in order to evaluate the daily relationships among emotional states, emotion regulation, alcohol consumption, and risky sexual behavior. Upon completion of the daily diary period, the same participants will complete an in-lab experiment assessing the in-the-moment effects of alcohol intoxication and emotional context on risky sexual intentions. Generalized estimating equations will be used to examine the daily influence of emotional states and emotion regulation strategies on alcohol consumption and sexual risk behavior. Structural equation modeling and other regression-based analyses will be used to examine the experimental effects of alcohol intoxication and experimentally- manipulated emotional context on sexual risk intentions.