Core C: Biogeochemistry Core Laboratory

项目总结（见说明）; 这一分析设施设在哥伦比亚大学的拉蒙特-多尔蒂地球观测站。生物地球化学核心将主要支持两个生物医学项目和三个非生物医学项目，并为社区参与核心和研究翻译核心提供额外支持。这一支助包括利用高分辨率电感耦合质谱法分析约24 000个地下水样品，不仅为生物医学项目1和2分析As和Mn，而且为非生物医学项目4分析地下水和沉积物沥滤物中的Na、Mg、Al、Si、P、S、K、Ca、Cr、Fe、Ni、Co、Cu、Zn、Mo、Cd、Sb、Ba、Pb和U。5，6，以及社区参与核心和研究翻译核心。核心C还支持通过液相色谱质谱法分析呼出气冷凝物样品中为项目2收集的生物标志物，并确定非生物医学项目的地下水和实验室样品子集中的As形态。为了分析美国超级基金场址和孟加拉国沉积物的整体化学性质，将系统地评价最新一代手持式X射线荧光分析仪的应用。在核心C项下还将支持地下水和沉积物中的大量有机碳测量。

PROJECT SUMMARY (See instructions); This analytical facility is housed at the Lamont-Doherty Earth Observatory of Columbia University. The Biogeochemistry Core will primarily support two biomedical projects and three non-biomedical projects, with additional support for the Community Engagement Core and the Research Translation Core. This support includes the analysis of ~24,000 groundwater samples by high-resolution inductively-couples mass spectrometry not only for As and Mn, on behalf of biomedical Projects 1 and 2, but also analysis of groundwater and sediment leaches for Na, Mg, Al, Si, P, S, K, Ca, Cr, Fe, Ni, Co, Cu, Zn, Mo, Cd, Sb, Ba, Pb and U on behalf of non-biomedical Projects 4, 5, 6, as well as the Community Engagement Core and the Research Translation Core. Core C also supports the analysis of exhaled breath condensate samples by liquid chromatography mass spectrometry for biomarkers collected for Project 2 and the determination of As speciation in a subset of groundwater and laboratory samples for the non-biomedical projects. For the analysis of the bulk chemistry of sediments from US Superfund sites and Bangladesh, the application of the latest generation of hand-held X-ray fluorescence analyzers will be systematically evaluated. Bulk organic carbon measurements in groundwater and sediment will also be supported under Core C.