P30 Core Grant for Vision Research

 描述(由申请者提供)：伊利诺伊大学芝加哥分校(UIC)的视觉科学研究项目得到了美国国家眼科研究所(NEI)运行时间最长的核心资助之一的支持。视觉研究中心核心助学金的首要目标是支持、加强和扩大UIC和邻近机构的基础和转化性视觉科学研究。中心核心补助金的一个主要优势是，它促进了视觉科学研究社区(VSRC)成员之间的跨学科、跨部门和跨机构的科学互动和合作。目前的VSRC调查人员总共拥有25项由NIH资助的研究资助，其中包括来自NEI的20项研究资助(其中12项是合格的R01)。中心核心资助资源对广泛和临床相关领域的开创性研究的绩效产生了重大影响。这些资源增强了个人研究人员的研究能力和生产力，创造了有利于资源共享和协作科学互动的环境，帮助新的研究人员开发研究项目，以及 帮助现有的研究人员在新兴领域进行研究。更新中心核心拨款申请回应了参与研究人员不断发展的研究需求，并请求资金支持5个资源核心：细胞和分子生物学核心、成像和图像分析核心、动物服务核心、仪器商店核心以及生物统计和遗传分析核心。这些资源核心提供了卓越的设施、尖端的生物仪器以及在分子生物学、细胞生物学、组织学、蛋白质组学、基因组学、成像、疾病建模、仪器、生物统计学和遗传分析方面的经验丰富的技术专长。中心核心赠款将继续支持和促进模范的基础和翻译跨学科和协作视觉科学研究的开展。它 将提供所需的基本催化剂，共同促进视觉系统的生物学和病理生理学知识，并开发预防视力丧失的新诊断和治疗方法。

 DESCRIPTION (provided by applicant): The vision science research program at the University of Illinois at Chicago (UIC) has been supported by one of the longest-running core grants from the National Eye Institute (NEI). The overarching goal of the Center Core Grant for Vision Research is to support, strengthen and expand basic and translational vision science research at UIC and neighboring institutions. A major advantage of the Center Core Grant is that it facilitates inter-disciplinary, inter-departmental, and inter-institutional scientific inteactions and collaborations among members of the Vision Science Research Community (VSRC). Current VSRC investigators hold a total of 25 NIH-funded research grants, consisting of 20 research grants from NEI (of which, 12 are qualifying R01s). The Center Core Grant resources have significantly impacted performance of pioneering research in wide-ranging and clinically-relevant areas. These resources have enhanced research capabilities and productivity of individual investigators, created an environment conducive to resource-sharing and collaborative scientific interactions, assisted new investigators to develop research projects, and aided established investigators to pursue research in emerging fields. This renewal Center Core Grant application responds to the evolving research needs of participating investigators and requests funding to support 5 resource Cores: Cellular and Molecular Biology Core, Imaging and Image Analysis Core, Animal Services Core, Instrument Shop Core, and Biostatistics and Genetic Analysis Core. These resource Cores provide exceptional facilities, cutting-edge bioinstrumentation, and experienced technical expertise in molecular biology, cellular biology, histology, proteomics, genomics, imaging, disease modeling, instrumentation, biostatistics, and genetic analysis. The Center Core Grant will continue to sustain and promote conduct of exemplary basic and translational inter- disciplinary and collaborative vision science research. It will provide the essential catalysts needed to collectively advance knowledge of the biology and pathophysiology of the visual system and develop novel diagnostic and therapeutic approaches for prevention of vision loss.