Training Program in Translational Cardiovascular Science

 申请者描述(由申请人提供)：本申请请求在16-20学年继续支持威斯康星大学麦迪逊分校医学院和公共卫生心血管研究中心(CVRC)的心血管科学(TPTCS)培训计划。CVRC是一个校园范围的跨学科研究中心，拥有来自七所学校和大学的31个系的教职员工和研究人员。所有这些机构都致力于开发基础研究、临床研究、诊断和治疗以及/或有关心血管疾病基础的公共教育项目。TPTCS培训计划为博士后博士和博士后(四个职位)以及博士前实习生(五个职位)提供基础研究培训，目标是培养能够从分子到床边进行思考和工作的科学家。实际的近期目标是吸引和培训基础研究方面的临床医生，并吸引和培训具有临床动机的基础科学方面的研究生和博士后(博士)学生。此应用程序请求支持医生的研究性培训，作为其住院医师和研究员培训的一部分。该培训计划还为翻译心血管科学的博士后和博士后学员提供资金。这项计划中的25名培训师是从CVRC成员中挑选出来的，依据的是他们在重点领域(收缩/心力、离子通道/心律失常和血管生物学/动脉粥样硬化)的临床相关性、他们的培训记录，以及他们同行评议的研究计划的总体稳健性和活动性。培训在威斯康星大学麦迪逊分校进行，利用这种培训的强大机构支持和环境，以及医学和公共卫生学院和整个大学临床和基础科学系和教员之间建立的工作关系。培训者和受训者都参加将TE方案定义为一个有凝聚力的实体的核心活动。科学家和内科科学家接受过这种翻译培训 心血管科学项目处于独特的地位，可以应用基本的科学知识来造福心血管疾病患者，心血管疾病是美国人死亡的首要原因。(摘要结束)

 DESCRIPTION (provided by applicant): This application requests continuing support for Years 16-20 for the Training Program in Translational Cardiovascular Science (TPTCS) within the School of Medicine and Public Health Cardiovascular Research Center (CVRC) at the University of Wisconsin-Madison. The CVRC is a campus-wide interdisciplinary research center with faculty and research members from 31 departments in seven schools and colleges. All are dedicated to developing programs in basic research, clinical investigation, diagnosis and therapy, and/or public education concerning the basis for cardiovascular diseases. The TPTCS training program provides basic research training for postdoctoral MDs and PhDs (four positions) as well as predoctoral trainees (five positions) with the goal of training scientists wh will be capable of thinking and working "from molecule to bedside." The practical immediate aims are to attract and train clinicians in basic research, and to attract and train graduate and postdoctoral (PhD) students in clinically motivated basic science. This application requests support for research training of physicians as part of their resident and fellow training. The training program also funds predoctoral and postdoctoral trainees in translational cardiovascular sciences. The 25 trainers in this program have been selected from members of the CVRC for the clinical relevance of their science in the focus areas (contractility/heart failure, ion channels/arrhythmias and vascular biology/atherosclerosis), their training records, and the overall robustness and activity of their peer-reviewed research programs. Training takes place at the University of Wisconsin-Madison and exploits the strong institutional support and environment for such training, as well as the established working relationships between clinical and basic science departments and faculty both within the School of Medicine and Public Health and the University at large. Trainers and trainees all participate in core activities that define te program as a cohesive entity. The scientists and physician scientists trained in this translational cardiovascular science program are in unique positions to apply basic scientific knowledge to benefit patients with cardiovascular disease, the foremost cause of mortality among Americans. (End of Abstract)