CSHL 2019 Eukaryotic mRNA Processing Conference

冷泉港实验室会议 真核生物mRNA加工 2019年8月20日至24日 摘要 拟议中的“真核mRNA加工”会议将召集科学家 研究mRNA加工、运输、周转和生物信息学的各个方面。 最近在所有这些领域都取得了重大进展， 会议将是一个及时的事件，讨论最新的未发表的结果， 交流思想，从而促进这一迅速发展的领域的新发展。的 拟议的会议将是每隔一段时间举行的系列会议中的第十二次会议。 在冷泉港实验室工作了一年。最近一次会议是在8月举行的 2017年吸引了329名国际科学家，他们正在积极研究各种 真核细胞中信使RNA成熟的方面，使用遗传，生物化学， 分子和细胞生物学方法。与前几次会议一样， 将在mRNA成熟的核事件，包括mRNA剪接， 多聚腺苷酸化，转录和mRNA成熟步骤之间的联系， 小RNA的生物发生和功能，信息学和全基因组的应用 分析RNA加工的方法，以及mRNA 癌症和其他疾病的病因学处理。我们提议八次全体会议 会议和两个海报会议。每一次全体会议将分为两次 部分（由咖啡休息时间分隔），专注于相关但独立的主题。在 对RNA修饰和RNA作用领域主要发展的回应 在处理过程中，我们扩大了专门讨论这些主题的会议;这 适应该领域的主要运动有助于保持这种会议在切割 优势，并确保我们将吸引来自传统和新兴市场的参与者， RNA研究领域。这一细分在2011年会议上成功试点， 允许更广泛的领域代表性，我们招募了一批不同的领导人， 在现场担任会议主席同以往一样，所有发言者都将根据 提交摘要，鼓励年轻科学家积极参与。我们将 特别鼓励学生展示未发表的作品， 博士后研究员领导这些项目，这在传统上是一个标志， 和冷泉港会议的独特优势。

COLD SPRING HARBOR LABORATORY CONFERENCE EUKARYOTIC mRNA PROCESSING AUGUST 20 - 24, 2019 ABSTRACT The proposed conference on “Eukaryotic mRNA Processing” will convene scientists studying various aspects of mRNA processing, transport, turnover and bioinformatics. Major advances have recently been made in all these areas, and the proposed conference will be a timely event for discussing the latest unpublished results and exchanging ideas, thereby fostering new developments in this rapidly moving field. The proposed conference will be the twelfth meeting in the series that is held every other year at Cold Spring Harbor Laboratory. The most recent meeting was held in August 2017 and attracted 329 scientists internationally, who are actively investigating various aspects of messenger RNA maturation in eukaryotic cells using genetic, biochemical, molecular, and cell biological approaches. As in the previous meetings, a major focus will be on nuclear events in mRNA maturation, including mRNA splicing and polyadenylation, the connections between transcription and mRNA maturation steps, small RNA biogenesis and function, the application of informatics and genome-wide approaches to the analysis of RNA processing, as well as the relevance of mRNA processing to the etiology of cancer and other diseases. We propose eight plenary sessions and two poster sessions. Each plenary session will be subdivided into two parts (separated by a coffee break) that focus on related but separate topics. In response to major developments in the fields of RNA modification and the roles of RNA structure in processing, we have expanded the sessions devoted to these topics; this adaptability to the major movements in the field helps keep this meeting at the cutting edge and ensures that we will draw participants from traditional as well as emerging areas of RNA research. This subdivision, successfully piloted at the 2011 meeting, allows a broader representation of fields and we have recruited a diverse set of leaders in the field as session chairs. As always, all speakers will be selected on the basis of the submitted abstracts, which encourages active participation by junior scientists. We will particularly encourage presentation of unpublished work by the students and postdoctoral fellows who are leading these projects, as has traditionally been a hallmark and a unique strength of the Cold Spring Harbor meetings.