Microfluidics in Biomedical Sciences Training Program

 描述（由申请人提供）：NIH支持的生物医学研究在很大程度上涉及分子、细胞和组织水平的复杂系统。这些生物学现象发生在微尺度（例如细胞的尺寸）和更小的尺度（例如蛋白质的尺寸）以及在水性流体环境下。该计划旨在满足生物医学和微流体交叉领域对训练有素的研究人员的需求。该培训计划的基本原理是，近年来生物医学和微流体接口的研究呈指数级增长。此外，除了学术研究的增长外，微流体在生物医学和生物技术行业的应用市场也呈指数级增长。在这样的背景下，该培训计划旨在通过以下方式为学员提供微流体和生物医学方面的双管齐下的技术/科学培训：（i）课程，（ii）双周研讨会，（iii）每月期刊俱乐部，（iv）年度研讨会，（v）以及第二实验室或行业的跨学科研究经验。这些核心NIH培训计划和活动将与生物医学科学学生组织（μFO）的微流体学和生物医学科学微流体学的拉克姆研究生证书计划密切相关。这为该计划提供了稳定性，使该计划的影响能够使更广泛的学生群体受益，而不是在此培训补助金上获得财政支持，并提高计划的知名度和加强招聘。选择这条道路的学生的行业实习安置将通过培训计划和成员教师和校友进行调解，并通过创业中心（CFE）和劳动，就业和经济研究所（IRLEE）的援助。实习生的任期将为2年，在博士前的水平。该计划每年将有7名活跃的受训人员，随着年龄较大的学生轮换，每年将有3或4名新学生加入。为了招募和留住多样化的学员，该计划的教师赞助夏季研究机会，参加少数民族会议，并培养和保持持续的个人和机构关系。学员还参加了密歇根大学开发的旗舰课程，该课程目前在全球范围内使用，涉及研究的道德和负责任行为。预期的培训成果是，该计划将培养微流体和生物医学领域的领导者，他们可以在技术和生命科学领域之间自由地发言和工作。所有学员将能够设计和使用微流体设备用于医学和生命科学应用。学员还将接受广泛的培训，以欣赏多样性，具有高标准的道德，并根据学员的兴趣接受学术或行业研究职业培训。

 DESCRIPTION (provided by applicant): Biomedical research supported by the NIH, to a significant extent, involves complex systems at the level of molecules, cells, and tissues. These biological phenomena occur at the microscale (e.g. size of cells) and smaller (e.g. size of proteins) and under an aqueous fluidic environment. This program aims to fill a need for trained researchers at the intersection of biomedicine and microfluidics. The rationale for this training program is that research at the interface of biomedicine and microfluidics has been increasing exponentially in recent years. Furthermore, in addition to academic research growth, the market for use of microfluidics in the biomedicine and biotechnology industry is also growing exponentially. With such a backdrop, this training program is designed to provide trainees with a two-pronged technical/scientific training in microfluidics and biomedicine through: (i) coursework, (ii) biweekly seminars, (iii) monthly journal club, (iv) annual symposia, (v) and an interdisciplinary research experience in a 2nd lab or in industry. These core NIH training programs and activities will be closely associated with the MicroFluidics in Biomedical Sciences Student Organization (μFO), and the Rackham Graduate Certificate Program in Microfluidics in Biomedical Sciences. This provides stability for the program, allows the program impact to benefit a much broader student population than can be supported financially on this training grant, as well as enhance program visibility and strengthen recruitment. Industry internship placement for students choosing that path will be mediated through the Training Program and member faculty and alumni, and also through assistance of the Center for Entrepreneurship (CFE) and Institute for Research on Labor, Employment, and the Economy (IRLEE). The duration of trainee appointments will be for 2 years at the pre-doctoral level. The program will have 7 active trainees per year with 3 or 4 new students coming in each year as older students rotate off. To recruit and retain a diverse cohort of trainees, the Program faculty sponsor summer research opportunities, attend minority conferences, and cultivate and maintain ongoing personal and institutional relationships. Trainees are also take a flagship course developed at the University of Michigan that is now used worldwide on Ethics and Responsible Conduct of Research. The intended trainee outcomes are that the program will produce leaders in microfluidics and biomedicine that can speak and work between technology and life sciences realms freely. All trainees will be able to design as well as use microfluidic device for medicine and life science applications. The trainees will also be broadly trained to appreciate diversity, have a high standard of ethics, and be trained for either academic or industry research career depending on trainee interests.