Administrative Supplement to Liquid Helium Recovery System for University of Delaware NMR Core
Administrative Supplement to Liquid Helium Recovery System for University of Delaware NMR Core
批准号:
9986137
负责人:
Colin Thorpe
金额:
$20.8万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1979
资助国家:
美国
项目状态:
已结题
起止时间:
1979-07-01 至 2022-06-30
关键词:
Administrative SupplementAwardBehaviorBiochemistryBiologicalChemistryChillsConsumptionDelawareDisulfidesDoctor of PhilosophyEquipmentFaceFundingHeliumInfrastructureInstitutesLaboratoriesLiquid substanceMonitorNMR SpectroscopyNational Institute of General Medical SciencesNuclear Magnetic ResonancePricePrincipal InvestigatorProteinsRecoveryResearchResearch PersonnelRunningScheduleShipsSiteSpecialistStructureSystemTechniquesTestingUnited States National Institutes of HealthUniversitiesWaterWorkbasebiomedical scientistcostinstrumentnoveloperationpreventsolid statetool
中文摘要
摘要
我们要求资金用于购买和安装液氦回收系统在我们的大学范围内的核
磁共振(NMR)核心,以支持正在进行的,并使新的,NIH资助的研究,由多个
特拉华州大学的调查员。位于化学和生物化学系磁铁大厅,
NMR Core支持校园内总共370多名研究人员的工作,这些研究人员来自50多个团体。
联邦资助的主要研究者,其中9人由NIGMS资助,4人由其他NIH研究所资助。大多数
的仪器运行在24/7的基础上。每年平均液氦消耗量约为4600升。是
根据90%的回收率,预计将回收4140升液氦。
核磁共振波谱是NIH资助研究的关键工具,依赖于尖端仪器的可用性
NMR核心的能力和不间断运行。全球氦气短缺已经有了一个
对我们的核磁共振基础设施造成了不利影响。在过去的12个月里,我们的氦气供应商普莱克斯
该公司一贯未能按时交付产品,未能提供所需数量,
我们的核磁共振磁铁的操作。考虑到全球氦气供应的减少,加上不断增加的
液氦价格,我们将很快面临的情况,我们将不得不关闭几个或全部的操作,
我们的乐器为了防止这种情况的发生,并确保我们的核磁共振设备的可持续长期运行,
安装液态氦回收系统已成为必要。
英文摘要
ABSTRACT
We request funds for the purchase and installation of a liquid helium recovery system in our University-wide Nuclear
Magnetic Resonance (NMR) Core, to support the ongoing, and enable new, NIH-funded research by multiple
investigators at the University of Delaware. Housed in the Department of Chemistry and Biochemistry Magnet Hall, the
NMR Core supports the work of a total of over 370 researchers on campus, coming from the groups of over 50
Federally funded Principal Investigators, of whom 9 are funded by NIGMS, and 4 by other NIH institutes. The majority
of the instruments run on a 24/7 basis. The average annual liquid helium consumption is about 4600 liters. It is
anticipated that 4140 liters of liquid helium will be recaptured based on a 90% recovery rate.
NMR spectroscopy is a critical tool for NIH-funded research and relies on the availability of cutting-edge instrument
capabilities and uninterrupted operation of the NMR Core. The worldwide helium shortage has already had a
detrimental impact on our NMR infrastructure. During the past 12 months, Praxair, our helium supplier, has
systematically failed to deliver the product on schedule and failed to supply the required amounts, jeopardizing the
operation of our NMR magnets. Given the dwindling helium supplies worldwide, compounded by the steadily increasing
price of liquid helium, we will soon face the situation that we will have to shut down the operation of several or all of
our instruments. To prevent this scenario and to assure sustainable long-term operation of our NMR equipment,
installation of a liquid He recovery system has now become essential.
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DOI:
10.1021/ja310553h
发表时间:
2013-02-20
期刊:
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
影响因子:
15
作者:
[Sapra, Aparna, Thorpe, Colin]
通讯作者:
Thorpe, Colin
Electron-transferring flavoprotein from pig kidney: flavin analogue studies.
来自猪肾的电子传递黄素蛋白:黄素类似物研究。
DOI:
10.1021/bi00370a050
发表时间:
1986
期刊:
Biochemistry
影响因子:
2.9
作者:
[Gorelick,RJ, Thorpe,C]
通讯作者:
Thorpe,C
Interflavin oxidation-reduction reactions between pig kidney general acyl-CoA dehydrogenase and electron-transferring flavoprotein.
猪肾酰基辅酶A脱氢酶与电子传递黄素蛋白之间的间黄素氧化还原反应。
DOI:
10.1021/bi00345a015
发表时间:
1985
期刊:
Biochemistry
影响因子:
2.9
作者:
[Gorelick,RJ, Schopfer,LM, Ballou,DP, Massey,V, Thorpe,C]
通讯作者:
Thorpe,C
Interaction of 3,4-dienoyl-CoA thioesters with medium chain acyl-CoA dehydrogenase: stereochemistry of inactivation of a flavoenzyme.
3,4-二烯酰基辅酶A硫酯与中链酰基辅酶A脱氢酶的相互作用:黄素酶失活的立体化学。
DOI:
10.1021/bi0109818
发表时间:
2001
期刊:
Biochemistry
影响因子:
2.9
作者:
[Wang,W, Fu,Z, Zhou,JZ, Kim,JJ, Thorpe,C]
通讯作者:
Thorpe,C
DOI:
10.1016/j.bbagen.2013.03.031
发表时间:
2014-02
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
影响因子:
3
作者:
[Winther, Jakob R., Thorpe, Colin]
通讯作者:
Thorpe, Colin
共 35 条
Flavoproteins in Oxidative Protein Folding
-
批准号:8059050
-
项目类别:
-
资助金额:$10.0万
-
财政年份:2010
-
负责人:Colin Thorpe
-
依托单位:
PROVIDE SMALL INSTRUMENTATION
-
批准号:2191071
-
项目类别:
-
资助金额:$1.49万
-
财政年份:1994
-
负责人:Colin Thorpe
-
依托单位:
SMALL INSTRUMENTATION GRANT
-
批准号:3524240
-
项目类别:
-
资助金额:$2.99万
-
财政年份:1992
-
负责人:Colin Thorpe
-
依托单位:
CONFERENCE--ENZYMES, COENZYMES & METABOLIC PATHWAYS
-
批准号:3435106
-
项目类别:
-
资助金额:$0.5万
-
财政年份:1990
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:3274046
-
项目类别:
-
资助金额:$10.02万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:2749793
-
项目类别:
-
资助金额:$20.23万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:3274042
-
项目类别:
-
资助金额:$9.37万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:6191443
-
项目类别:
-
资助金额:$30.66万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
Flavoproteins in Oxidative Protein Folding
-
批准号:8685269
-
项目类别:
-
资助金额:$33.66万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
Flavoproteins in Oxidative Protein Folding
-
批准号:9171987
-
项目类别:
-
资助金额:$35.35万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:2174748
-
项目类别:
-
资助金额:$19.44万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:6018504
-
项目类别:
-
资助金额:$21.08万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:3274043
-
项目类别:
-
资助金额:$11.8万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:3274041
-
项目类别:
-
资助金额:$8.61万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:6385363
-
项目类别:
-
资助金额:$26.25万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
Flavoproteins in Oxidative Protein Folding
-
批准号:6818592
-
项目类别:
-
资助金额:$29.56万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
Flavoproteins in Oxidative Protein Folding
-
批准号:8096532
-
项目类别:
-
资助金额:$32.24万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
Flavoproteins in Oxidative Protein Folding
-
批准号:8502669
-
项目类别:
-
资助金额:$32.48万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
Flavoproteins in Oxidative Protein Folding
-
批准号:8366924
-
项目类别:
-
资助金额:$33.66万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
FLAVOPROTEINS IN FATTY ACID METABOLISM
-
批准号:6618123
-
项目类别:
-
资助金额:$26.25万
-
财政年份:1979
-
负责人:Colin Thorpe
-
依托单位:
海外基金