Administrative Core

抽象行政核心 这项申请的主要目的是“扩大俄克拉荷马州发育生物学的卓越水平” (俄克拉荷马州发育生物学科布雷)，是为了加强我们在 俄克拉荷马州医学研究基金会(OMRF)并为该中心和核心做好可持续发展的准备 科布雷基金结束了。我们将通过以下途径扩大和加强我们在发育生物学方面的现有专业知识 支持试点项目并扩大我们两个科学核心(成像)的技术和专业知识 和生物信息学与路径)。为支持这些目标，行政核心将作为 俄克拉荷马州发育生物学眼镜蛇的集中协调资源。核心总监将 促进俄克拉荷马州试点项目调查员及其导师之间的沟通，监督 核心的运作，确保遵守国家卫生研究院的所有政策，并为科学发展提供基础 基础发育生物学和翻译发育生物学研究。行政核心主任将是主要的 科布雷网络和美国国立卫生研究院的联系人。为了实现这些目标，行政核心将专注于 关于以下具体目标： 目标1.为俄克拉荷马州发育生物学眼镜蛇组件提供集中管理 活动。目标2.成立一个指导委员会，以评估科布雷的运作并提供咨询意见 给私家侦探。目标3.成立一个国际公认的发展问题外部咨询委员会 生物学家对试点项目调查人员的进展和科学核心的有效性进行评估。 目标4.促进多学科的研究方法和科布雷调查人员之间的互动 通过一个充满活力的每月研讨会计划。目标5.为之前的第一阶段和 科布雷第二阶段调查人员。目的6.促进俄克拉荷马州发育生物学的相互作用 科布雷与其他科布雷和国家计划。目标7.提供财政管理 科布雷和合规监管问题。目标8.促进数据共享战略。

ABSTRACT ADMINISTRATIVE CORE The primary purpose of this application, “Expanding Excellence in Developmental Biology in Oklahoma” (Oklahoma Developmental Biology COBRE), is to strengthen our Developmental Biology Center at the Oklahoma Medical Research Foundation (OMRF) and to prepare the Center and Cores for sustainability after COBRE funding ends. We will expand and strengthen our existing expertise in Developmental Biology through the support of Pilot Projects and expansion of technologies and expertise in our two Scientific Cores (Imaging and Bioinformatics and Pathways). In support of these goals, the Administrative Core will serve as the centralized coordinating resource for the Oklahoma Developmental Biology COBRE. The Core Director will facilitate communication among the Oklahoma Pilot Project Investigators and their Mentors, monitor the functioning of the Cores, ensure compliance with all NIH policies, and provide a foundation for scientific growth in basic and translational Developmental Biology research. The Administrative Core Director will be the primary contact for the Network of COBREs and the NIH. To accomplish these goals, the Administrative Core will focus on the following Specific Aims: Aim 1. To provide central management for the Oklahoma Developmental Biology COBRE components and activities. Aim 2. To form a Steering Committee to evaluate the functioning of the COBRE and provide advice to the PI. Aim 3. To form an External Advisory Committee of internationally recognized Developmental Biologists to evaluate the progress of the Pilot Project Investigators and effectiveness of the scientific Cores. Aim 4. To promote multidisciplinary approaches to research and interactions among the COBRE investigators through a vigorous monthly seminar program. Aim 5. To provide continued mentoring to previous Phase I and Phase II COBRE investigators. Aim 6. To facilitate interactions of the Oklahoma Developmental Biology COBRE with other COBREs and with the national program. Aim 7. To provide fiscal management of the COBRE and compliance with regulatory issues. Aim 8. To promote data sharing strategies.