Cancer Biology Training Program

项目摘要 我们要求为我们的T32再提供五年的资金，以支持基础广泛的、跨部门的预科和 德克萨斯大学圣安东尼奥健康科学中心癌症生物学博士后培训 (UTHSA)，一家指定的拉美裔服务机构。在下一个供资期间(11-15年)，我们要求3 博士后空位和博士后空位。我们的癌症生物学培训项目是NCI资助的唯一一个T32项目， UTHSA。我们提供在癌症研究和发现方面的强化和严格的培训 经验丰富的导师和职业发展机会，为积极进取的研究生和 博士后研究员，特别是那些来自生物医学研究中代表性不足(UR)群体的研究员。 自2011年8月首次授予T32以来，所有实习生职位(每个职位1名博士后和3名博士后 获奖年度)已经满员，受训人员的工作效率很高。到目前为止，有7名博士后和15名博士后 博士后研究员被任命为T32实习生，41%(2名博士后和7名博士后)是URS。这个 培训计划将继续由同一主任和联席主任领导，并由新的联合主任- 董事，并由经验丰富的执行委员会监督。培训人员五花八门，共有19名 来自9个系的教授和5名副教授，7名助理教授作为共同导师。全 培训教师在研究生院和我们NCI指定的梅斯癌症中心拥有完全的教职员工特权 (MCC)。我们的培训人员与众多合作出版物高度互动，资金雄厚 研究组合(本年度每个导师的平均直接成本&>87万美元)，以及经验丰富和 成功指导博士后和博士后实习生。许多针对培训计划的新活动 利用不断增长的基础、转化和临床癌症研究机会(特别是在MCC) 生物信息学、药物开发和前沿共享资源。年度务虚会和双月务虚会 学员的午餐将允许学员展示他们的研究进展并与该计划互动 联席主任、培训教员、外部咨询委员会和其他受训人员，包括 完成了培训。课程还包括科学交流方面的培训和 负责任地进行研究以及严谨和可重复性。受训者将被选为他们的 学术成就和对癌症研究的奉献精神，任期为2年。的确有 对该培训计划的重大机构承诺，例如对计划主任的工资支持，以及 MCC对第四名博士前实习生的匹配支持。我们的癌症生物学培训计划寻求 这将继续对下一代独立调查员的多样性作出贡献 努力实现NCI改善癌症预防、检测、诊断、治疗和治疗的目标 生存能力。

Project Summary We request a further five years of funding for our T32 to support broad-based, interdepartmental pre- and postdoctoral training in cancer biology at the University of Texas Health Science Center at San Antonio (UTHSA), a designated Hispanic-Serving Institution. In this next funding period (years 11-15), we request 3 predoctoral slots and 3 postdoctoral slots. Our Cancer Biology Training Program is the only NCI-funded T32 at UTHSA. We provide intensive and rigorous training in cancer research and discovery under the tutelage of seasoned preceptors and professional development opportunities to highly motivated graduate students and postdoctoral research fellows, especially those from groups underrepresented (UR) in biomedical research. Since this T32 was first awarded in August 2011, all trainee positions (1 predoctoral and 3 postdoctoral in each award year) have been filled, and trainees have been highly productive. To date, 7 predoctoral students and 15 postdoctoral fellows have been appointed as T32 trainees, and 41% (2 predocs and 7 postdocs) are URs. The Training Program will continue to be directed by the same Director and Co-Director, enhanced by a new Co- Director, and overseen by a seasoned Executive Committee. The training faculty is diverse, with 19 full professors and 5 associate professors, and 7 assistant professors as Co-Mentors, from 9 departments. All training faculty have full faculty privileges in the Graduate School and our NCI-designated Mays Cancer Center (MCC). Our training faculty are highly interactive with numerous collaborative publications, have strong funded research portfolios (average direct costs >$870K per mentor in the current year), and are experienced and successful in mentoring predoctoral and postdoctoral trainees. Many new Training Program-specific activities leverage growing basic, translational and clinical cancer research opportunities (especially at the MCC) in bioinformatics, drug development, and cutting-edge shared resources. Annual Retreats and bi-monthly Trainees’ Luncheons will allow trainees to showcase their research advances and interact with the Program Co-Directors, the training faculty, the External Advisory Board, and other trainees, including those who have completed training. The curriculum also includes training in scientific communication and a strong base in responsible conduct of research as well as rigor and reproducibility. Trainees will be selected for their academic accomplishments and their dedication to cancer research and will be appointed for 2 years. There is substantial institutional commitment to this Training Program, e.g. salary support for the Program Director, and matching support from the MCC for a fourth predoctoral trainee. Our Cancer Biology Training Program seeks this continuation to continue its contribution to diversity in the next generation of independent investigators working to accomplish NCI’s goal of improving cancer prevention, detection, diagnosis, treatment, and survivorship.