Integrated Neural Engineering and Rehabilitation Training Program
Integrated Neural Engineering and Rehabilitation Training Program
批准号:
10838108
负责人:
Jeffrey R Capadona
金额:
$10.76万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-07-01 至 2024-08-31
中文摘要
这份建议书描述了我们的“综合神经工程和康复训练”计划,
培养生物医学工程博士毕业生,他们结合了最先进的神经工程专业知识
(生物工程领域),真正了解临床康复的实践和挑战。
这款T32是凯斯西储大学生物医学工程系的中心,但也
包括我们当地几个医疗中心的大力参与。我们的T32专门专注于
博士前培训-自1999年以来已培训了76名学生。我们正在申请2个补充项目的资金
博士前职位为期一年,机构资金支持他们参加培训计划的第二年。
我们预计每年将培养8名BME博士生,这是我们项目的补充。实习生
接受工程或相关学科的本科培训。他们满足了严格的
符合BME博士项目的要求,并受益于其现有功能,同时我们的T32项目增加了价值
通过高度协作和跨学科的研究项目、临床沉浸体验和独特的
访问访问研讨会的演讲者。我们正在创建一门基于虚拟现实的神经解剖课程(利用
我们与Microsoft HoloLens计划的独特关系),包括正式和非正式的多样性培训,
以及通过更多具有行业经验的教师、代表性不足的培训师来实现导师队伍的多元化,以
促进招募和培训妇女、少数民族和贫困学生参加该计划。
我们培训计划的具体目标是:(1)为我们的受训人员在以下领域的职业生涯做好准备
康复和神经工程学;(2)提供严谨的工程学教育,为未来奠定基础
创新;(3)在神经刺激的开发和应用方面提供专门知识和
克服神经障碍的干预措施;(4)提供建模和模拟方面的专门知识;
(5)提供广泛的、亲身实践的临床沉浸体验,为每个实习生准备翻译
职业;(6)在脑机接口的部署和集成方面提供专门知识;及(7)
提供现实世界的专业发展培训,以提高毕业后的成功。
我们已经组建了一个杰出的导师团队,他们担任以下三个角色之一:研究培训
作为受训者主要研究顾问的导师(17人)、副研究培训导师(5人)
他们是T32学员委员会的内容专家,以及康复和临床培训导师(12人)
确保每个受训人员研究项目的临床相关性的外科学科。我们正在进行
增加新的导师(3),以进一步多样化导师库。实习生项目主题包括电极
发展;脑机接口;感觉恢复;疼痛管理;刺激模式设计;
神经运动控制机制;神经生物材料、保护和修复;对患有
神经障碍;神经康复;建模和模拟;以及脑机接口。
英文摘要
This proposal describes our “Integrated Neural Engineering and Rehabilitation Training” program that
produces biomedical engineering Ph.D. graduates who combine state-of-the-art expertise in neural engineering
(an area of bioengineering) with a genuine appreciation of the practice and challenges of clinical rehabilitation.
This T32 is centered in the Department of Biomedical Engineering at Case Western Reserve University, but also
includes the strong participation of several of our local medical centers. Our T32 is focused exclusively on
predoctoral training - having trained 76 students since 1999. We are requesting funding for 2 supplemental
predoctoral positions for one year, with institutional funds to support their second year in the training program.
We expect to train a total 8 BME Ph.D. students per year with this added supplement to our program. Trainees
enter with undergraduate training in engineering or a closely related discipline. They satisfy the rigorous
requirements of the BME Ph.D. program and benefit from its existing features, while our T32 program adds value
through highly collaborative and interdisciplinary research projects, a clinical immersion experience, and unique
access to visiting seminar speakers. We are creating a virtual reality-based Neural Anatomy course (exploiting
our unique relationship with the Microsoft HoloLens program), including formal and informal diversity training,
and diversifying out mentoring pool with more faculty with industry experience, underrepresented trainers, to
facilitate the recruitment and training of women, minorities, and disadvantaged students to the program.
The specific objectives of our training program are: (1) Prepare our trainees for productive careers in
rehabilitation and neural engineering; (2) Provide a rigorous engineering education that forms the basis for future
innovation; (3) Provide specific expertise in the development and application of neural stimulation and
interventions for overcoming neurological disorders; (4) Provide specific expertise in modeling and simulation;
(5) Provide an extensive, hands-on clinical immersion experience that prepares each trainee for a translational
career; (6) Provide specific expertise in the deployment and integration of Brain Computer Interfaces; and (7)
Provide real-world professional development training to enhance post-graduation success.
We have assembled a distinguished group of mentors who serve in one of three roles: Research Training
mentors (17) who are the primary research advisors of the trainees, Associate Research Training Mentors (5)
who are content experts on T32 trainee committees, and Clinical Training Mentors (12) from rehabilitation and
surgical disciplines who insure the clinical relevance of each trainee research project. We are in the process of
adding new mentors (3) to further diversity the mentor pool. Trainee project topics include electrode
development; brain computer interfacing; sensory restoration; pain management; stimulation pattern design;
neural motor control mechanisms; neural biomaterials, protection, and repair; interventions to individuals with
neurological disorders; neurorehabilitation; modeling and simulation; and brain-computer interfacing.
期刊论文(74)
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Case study: Head orientation and neck electromyography for cursor control in persons with high cervical tetraplegia.
案例研究:头部方向和颈部肌电图用于高位颈椎四肢瘫痪患者的光标控制。
DOI:
10.1682/jrrd.2014.10.0244
发表时间:
2016
期刊:
Journal of rehabilitation research and development
影响因子:
--
作者:
[Williams,MatthewR, Kirsch,RobertF]
通讯作者:
Kirsch,RobertF
DOI:
10.1109/tnsre.2008.2003390
发表时间:
2008-10
期刊:
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
影响因子:
--
作者:
[Fisher LE, Miller ME, Bailey SN, Davis JA Jr, Anderson JS, Rhode L, Tyler DJ, Triolo RJ]
通讯作者:
Triolo RJ
DOI:
10.3389/fnbot.2022.902162
发表时间:
2022
期刊:
FRONTIERS IN NEUROROBOTICS
影响因子:
3.1
作者:
[Segil, Jacob L., Roldan, Leah Marie, Graczyk, Emily L.]
通讯作者:
Graczyk, Emily L.
Reconnecting the Hand and Arm to the Brain: Efficacy of Neural Interfaces for Sensorimotor Restoration after Tetraplegia.
将手和手臂重新连接到大脑:神经接口对四肢瘫痪后感觉运动恢复的功效。
DOI:
10.1101/2023.04.24.23288977
发表时间:
2023
期刊:
medRxiv : the preprint server for health sciences
影响因子:
--
作者:
[Herring,EricZ, Graczyk,EmilyL, Memberg,WilliamD, Adams,RobertD, Baca-Vaca,GuadalupeFernandez, Hutchison,BriannaC, Krall,JohnT, Alexander,BenjaminJ, Conlan,EmilyC, Alfaro,KenyaE, Bhat,PreethiR, Ketting-Olivier,AaronB, Haddix,Chase]
通讯作者:
Haddix,Chase
Evaluation of head orientation and neck muscle EMG signals as three-dimensional command sources.
评估头部方向和颈部肌肉肌电图信号作为三维命令源。
DOI:
10.1186/s12984-015-0016-6
发表时间:
2015
期刊:
Journal of neuroengineering and rehabilitation
影响因子:
5.1
作者:
[Williams,MatthewR, Kirsch,RobertF]
通讯作者:
Kirsch,RobertF
共 43 条
Optimizing Delivery of a Known Therapeutic Agent, Dexamethasone, to Improve Microelectrode Recording Performance
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批准号:10418649
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项目类别:
-
资助金额:$0.0万
-
财政年份:2020
-
负责人:Jeffrey R Capadona
-
依托单位:
Optimizing Delivery of a Known Therapeutic Agent, Dexamethasone, to Improve Microelectrode Recording Performance
-
批准号:10642761
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项目类别:
-
资助金额:$0.0万
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财政年份:2020
-
负责人:Jeffrey R Capadona
-
依托单位:
Optimizing Delivery of a Known Therapeutic Agent, Dexamethasone, to Improve Microelectrode Recording Performance
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批准号:10217285
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项目类别:
-
资助金额:$0.0万
-
财政年份:2020
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负责人:Jeffrey R Capadona
-
依托单位:
RR&D Research Career Scientist Award Application
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批准号:10060750
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
RR&D Research Career Scientist Award Application
-
批准号:10533265
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项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
RR&D Research Career Scientist Award Application
-
批准号:10311087
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项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
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依托单位:
Characterizing and Mitigating the Role of Oxidative Damage in Microelectrode Failure
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批准号:10599364
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项目类别:
-
资助金额:$58.11万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
Hybrid Drug-Eluting Microfluidic Neural Probe for Chronic Drug Infusion
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批准号:10356848
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项目类别:
-
资助金额:$0.0万
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财政年份:2019
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负责人:Jeffrey R Capadona
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依托单位:
Characterizing and mitigating the role of oxidative damage in microelectrode failure
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批准号:10561933
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项目类别:
-
资助金额:$11.42万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
Hybrid Drug-Eluting Microfluidic Neural Probe for Chronic Drug Infusion
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批准号:10840055
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项目类别:
-
资助金额:$0.0万
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财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
Senior Research Career Scientist
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批准号:10749218
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项目类别:
-
资助金额:$0.0万
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财政年份:2019
-
负责人:Jeffrey R Capadona
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依托单位:
Characterizing and mitigating the role of oxidative damage in microelectrode failure
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批准号:9894871
-
项目类别:
-
资助金额:$63.6万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
Characterizing and Mitigating the Role of Oxidative Damage in Microelectrode Failure
-
批准号:10374024
-
项目类别:
-
资助金额:$58.21万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
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依托单位:
Characterizing and Mitigating the Role of Oxidative Damage in Microelectrode Failure
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批准号:10812144
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项目类别:
-
资助金额:$11.42万
-
财政年份:2019
-
负责人:Jeffrey R Capadona
-
依托单位:
Antioxidative Microelectrodes to Improve Neural Recording Performance
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批准号:10179504
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项目类别:
-
资助金额:$0.0万
-
财政年份:2018
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负责人:Jeffrey R Capadona
-
依托单位:
Antioxidative Microelectrodes to Improve Neural Recording Performance
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批准号:10426077
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项目类别:
-
资助金额:$0.0万
-
财政年份:2018
-
负责人:Jeffrey R Capadona
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依托单位:
Resveratrol Prevents Microelectrode Mediated Neurodegeneration
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批准号:9253032
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项目类别:
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资助金额:$0.0万
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财政年份:2014
-
负责人:Jeffrey R Capadona
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依托单位:
Resveratrol Prevents Microelectrode Mediated Neurodegeneration
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批准号:9001843
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项目类别:
-
资助金额:$0.0万
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财政年份:2014
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负责人:Jeffrey R Capadona
-
依托单位:
CD14 facilitates neural device integration and performance
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批准号:8632462
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项目类别:
-
资助金额:$45.05万
-
财政年份:2013
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负责人:Jeffrey R Capadona
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依托单位:
CD14 facilitates neural device integration and performance
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批准号:8875788
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项目类别:
-
资助金额:$45.05万
-
财政年份:2013
-
负责人:Jeffrey R Capadona
-
依托单位:
海外基金