Training Program in the Molecular Bases of Eye Disease

描述：（申请人的摘要）一个博士后培训计划， 促进研究解决眼睛疾病的潜在分子基础， 是由哈佛医学院的眼科部门创建的。 该计划旨在提供最新分子生物学领域的专业知识。 研究技术，并使受训者了解 眼科突出问题。32名教师导师， 在哈佛眼科的任职或隶属关系 医学院，是从实验室的马萨诸塞州眼耳 医务室、舍彭斯眼科研究所、布里格姆和妇女医院 医院，长木校园基础科学部门和部门 分子与细胞生物学在剑桥校园。这些导师命令 资金充足的项目，眼科和视力研究的研究机会 使用现代分子技术，并拥有一流的设备。自1997年以来， 培训计划启动时， 在过去的一个月里，有3名新学员被录取。每个 受训人员预计将接受两至三年的培训。受训人员（一） 参与全职研究，以掌握分子技术 生物化学、细胞生物学、遗传学、免疫学或神经生物学 眼科和视觉;（ii）获得眼科问题的培训 通过一系列的教学课程，临床大查房，研讨会，期刊 （iii）申请及提交拨款申请， 第二年和第三年培训的个别支助， 一门关于资助申请原则的正式课程。在这次更新申请中， 我们寻求支持，将我们的计划再延长五年。我们建议 在此期间，每年招收的学员人数增加至9人。 期间，并扩大申请人池，包括MD和DVM谁拥有 完成了他们的眼科培训我们的目标是训练下一个 培养能够解决诊断，预防， 以及治疗眼部疾病。

DESCRIPTION: (Applicant's Abstract) A postdoctoral training program that fosters research addressing the underlying molecular basis of eye diseases has been created through the Department of Ophthalmology at Harvard Medical School. The program is designed to provide expertise in the most current molecular research techniques and to equip the trainees with a knowledge of the outstanding problems in ophthalmology. Thirty-two faculty mentors, all with appointments or affiliations with the Department of Ophthalmology at Harvard Medical School, are drawn from laboratories of the Massachusetts Eye and Ear Infirmary, the Schepens Eye Research Institute, the Brigham and Women's Hospital, the Longwood Campus Basic Science Departments and the Department of Molecular and Cellular Biology on the Cambridge Campus. These mentors command well funded programs, research opportunities for ophthalmic and vision research using current molecular techniques, and have excellent facilities. Since 1997, when the Training Program was initiated, 10 trainees have matriculated, and 3 new trainees have been admitted within the past month. Each trainee is expected to spend two to three years in training. Trainees (i) participate in full-time research to obtain a mastery of molecular techniques in biochemistry, cell biology, genetics, immunology, or neurobiology as applied to ophthalmology and vision; (ii) acquire training in ophthalmic problems through a series of didactic courses, clinical grand rounds, seminars, journal clubs, meetings; and (iii) write and submit grant proposals to obtain individual support for second and third year of training under the guidance of a formal course in principles of grant submission. In this renewal application, we seek support to extend our program for five additional years. We propose to increase the number of trainees admitted per year to 9 over the course of this period, and to expand the applicant pool to include MDs and DVMs who have completed their ophthalmology training. Our goal is to train the next generation of investigators who can address problems of diagnoses, prevention, and treatment of diseases of the eye.