Institute Training Grant in Pediatric Gastroenterology

描述(由申请人提供)： 这是儿科胃肠病学机构培训计划的新申请，旨在培养受过培训的研究人员，以便在儿科胃肠病学领域的基础或临床研究中取得成功。受训者将处于博士后水平，通常拥有医学博士学位，支持两年的基础或临床研究培训。这笔赠款允许每年招聘两名医学博士或博士实习生，每人总共接受两年的培训。该计划将把重点放在基础科学研究的几个方面，包括分子生物学、免疫学、病毒学和肝细胞损伤的机制。纳入这些方法的理由是，它们在儿科胃肠病学和发育生物学的研究中越来越重要。导师(15名医学博士，2名医学博士，7名博士)代表了一个多学科小组，他们对直接适用于儿科胃肠病学的研究领域表现出了浓厚的兴趣。此外，他们还在培养临床科学家或临床研究水平的医生方面取得了成功。科罗拉多大学的儿科胃肠病、肝病和营养计划在培训学术医生方面有着良好的记录，所有研究员都接受了至少两年的专门研究培训。这项申请旨在为竞争异常激烈的其他申请者增加基础和临床研究项目的资金。行政决定的性质(挑选受训人员、挑选导师和研究项目)由方案主任通过遴选和研究委员会进行指导。对MD研究员的培训包括为研究技术入门而设计的课程工作，以及通过科罗拉多大学健康科学中心在临床研究方面的小型证书计划。每个研究员都有一个指定的导师和研究委员会，并被要求提交一份书面研究计划，并定期审查进展情况。学员是从科罗拉多大学竞争激烈的申请者中挑选出来的。这项计划已经证明了成功，55%的医学博士仍然活跃在研究中，并成功地获得了研究资金。这项提议将扩大这一计划在培养未来学术儿科胃肠病专家方面取得的历史性成功。

DESCRIPTION (provided by applicant): This is a new application for an institutional training program in Pediatric Gastroenterology designed to produce investigators trained for a successful career in basic or clinical research in the area of pediatric gastroenterology. Trainees will be at the post-doctoral level, generally with an MD, supported for two years of basic or clinical research training. This grant allows for recruitment of two MD or PhD trainees each year for a total of two years of training each. The program will place a strong emphasis on several pathways of basic science research including molecular biology, immunology, virology and mechanisms of liver cell injury. The rationale for inclusion of these approaches is that they are increasingly important in research in pediatric gastroenterology and developmental biology. The mentors (15 MD's, 2 MD/PhD's, 7 PhD's) represent a multidisciplinary group with a demonstrated focused interest in areas of research that are directly applicable to pediatric gastroenterology. In addition, they have demonstrated success at training clinician scientists or clinical research level physicians. The Pediatric Gastroenterology, Hepatology and Nutrition Program at the University of Colorado has an excellent track record in training academic physicians with all fellows receiving at least two years of dedicated research training. This application seeks to increase funding for basic and clinical research programs for an exceptionally competitive pool of fellow applicants. The nature of administrative decisions (selection of trainees, selection of mentors and research projects) are directed by the Program Director through the Selection and Research Committees. The training for MD fellows includes course work designed for introduction to research techniques and the Mini-Certificate program in Clinical Research through the University of Colorado Health Sciences Center. Each fellow has a designated mentor and research committee, and is required to present a written research proposal, and undergoes periodic reviews of progress. The trainees are selected from a competitive applicant pool at the University of Colorado. This program has demonstrated success with 55% of MD's remaining active in research with success in research funding. This proposal will allow amplification of the historic success of this program in training future academic pediatric gastroenterologists