High-Voltage Compact Capacitor for Implantable Defibrillator

描述（由申请人提供）：用于植入式除颤器的高压紧凑型电容器在全球范围内，心脏骤停是一个主要的健康问题。植入式心律转复除颤器（ICD）的使用已成为一种越来越被接受的治疗选择，每年可以挽救数千名心脏病发作患者。随着这些器械接受度的提高，对ICD功能和材料改进的推动力也在加强。该项目计划的总体目标是为下一代植入式除颤器开发一种新型全固态高压电容器。该SBIR第一阶段将展示一种新颖且廉价的方法，用于制造具有更高工作电压和体积能量密度的ICD应用的全固态高能量密度电容器。目的是提高现有Giner公司的工作电压。高压全固态电化学电解电容器。这将使ICD内所需电容器的数量从四个减少到两个，通过用固体电解质代替液体电解质来减少ICD的重量和体积，允许使用双极多电池串联设计来实现高电压，并且消除分流电流和电解质泄漏的任何可能性，从而提高可靠性和安全性。将制造原型电容器单元，并对其进行表征和测试。这些单位将与标准电容器进行比较，以评估项目的整体效益。包装战略将与行业领导者合作制定和确定。一个单位电容器将被制造和操作，以证明概念的可行性。第II阶段将扩大调查范围，以优化和标准化工艺和设计，a）制造最终电池组，评估电容器外壳、封装材料和程序，B）进行长期稳定性和生物相容性测试，以及c）研究和选择灭菌和包装选项。公共卫生相关性 植入式心律转复除颤器（ICD）的使用已成为一种越来越被接受的治疗选择，每年可以挽救数千名心脏病发作患者。迫切需要用于ICD的尺寸减小的高能量密度电容器。ICD内电容器体积和重量的大幅减少将代表ICD的显著产品改进，从而为患者带来许多优势。

DESCRIPTION (provided by applicant): High voltage Compact Capacitor for Implantable Defibrillator Worldwide, sudden cardiac arrest is a major health problem. The use of Implantable Cardioverter Defibrillators (ICD) has become an increasingly accepted treatment option, one that could save thousands of heart attack patients annually. With the increase in acceptance of these devices, the drive for improvement of ICD function and materials has intensified. The overall objective of the project program is to develop a new all solid high voltage capacitor type for the next generation of implantable defibrillators. This SBIR Phase I will demonstrate a novel and inexpensive method for the manufacture of an all-solid high energy density capacitor for ICD applications with higher operating voltages and volumetric energy densities. The objective is to increase the operating voltage of the existing Giner, Inc. high-voltage all-solid electrochemical-electrolytic capacitor. This will reduce the number of required capacitors inside the ICD from four to two, reduce the ICD weight and volume by replacing liquid electrolyte with solid electrolyte, permit use of a bipolar multi-cell series design to achieve high voltages, and, eliminate any possibility of shunt currents and electrolyte leakage, thereby enhancing reliability and safety. Prototype capacitor cells will be fabricated and characterized and tested. These units will be compared to standard capacitors to assess the overall benefit of the project. Packaging strategies will be developed and identified in collaboration with an industry leader. A unit capacitor will be fabricated and operated to demonstrate concept feasibility. Phase II will extend the investigation to optimize and standardize processes and designs to a) fabricate final cell stacks, evaluate capacitor housings, encapsulation materials, and procedures, b) perform long-term stability and biocompatibility tests, and to, c) study and select sterilization and packaging options. PUBLIC HEALTH RELEVANCE The use of Implantable Cardioverter Defibrillators (ICD) has become an increasingly accepted treatment option, one that could save thousands of heart attack patients annually. There is critical need for reduced size, high energy density capacitor for the ICD. Substantial reduction in the volume and consequently weight of the capacitor inside the ICD would represent a significant product improvement ICD resulting in many advantages for the patients.