SUBSTANCE ABUSE BEHAVIOR

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项调查的目的是比较轻度和重度社交饮酒者对酒精的独特行为和生理反应及其相关性。我们计划在一项临床前实验室研究中明确他们的目标、表现和主观酒精反应。将在血液酒精浓度上升和下降期间采取措施，以便更好地了解重度酒精使用的早期阶段涉及的潜在因素。我们还计划在研究的临床前阶段之后对研究参与者进行几年的跟踪调查，以检查急性酒精反应因素是否与未来的饮酒模式和酒精后果显著相关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this investigation is to compare unique behavioral and physiological responses to alcohol and their associations in light and heavy social alcohol drinkers. We plan to specify their objective, performance, and subjective alcohol response in a preclinical laboratory study. Measures will be obtained during both rising and declining blood alcohol concentrations in order to better understand potential factors involved in the earlier stages of heavy alcohol use. We also plan to follow-up on study participants for several years after the preclinical phase of the study to examine whether acute alcohol response factors are significantly associated with future drinking patterns and alcohol consequences.