STUDIES OF RUBREDOXIN BY PARAMAGNETIC 15N NMR SPECTROSCOPY
STUDIES OF RUBREDOXIN BY PARAMAGNETIC 15N NMR SPECTROSCOPY
批准号:
7598667
负责人:
JOHN LUTE MARKLEY
金额:
$0.31万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-03-01 至 2008-02-29
关键词:
Computer Retrieval of Information on Scientific Projects DatabaseFundingGrantHydrogen BondingInstitutionLiquid substanceMicellesMutagenesisObject AttachmentPropaneReportingResearchResearch PersonnelResourcesRubredoxinsSiteSourceSpectrum AnalysisTemperatureUnited States National Institutes of Healthmutant
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
最近,人们研究了几种CP rubredosin氢键的定点突变,并报道了这些突变体的还原潜力。顺磁核磁共振可以很好地研究与CP Rebredosin还原电位相关的氢键。此外,液体丙烷中反胶束中的卢布还蛋白为超精细位移提供了更广泛的温度依赖研究。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Several site-mutagenesis on hydrogen bonds of Cp rubredoxin have been studied and reduction potentials of these mutants are reported recently. Paramagnetic NMR is powerful to examine the H bonds associated with reduction potential of Cp rebredoxin. In addition, rubredoxin in reverse micelles in liquid propane provides the wider temperature-dependent study of hyperfine shifts.
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资助金额:$35.94万
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依托单位:
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NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY SERUM ANALYSIS
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ROUTINE WEEKLY SPECTROMETER MAINTENANCE AND LIQUID NITROGEN FILLS
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依托单位:
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负责人:JOHN LUTE MARKLEY
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海外基金