HIGH RISK BREAST CANCER CLINIC

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 高风险乳腺癌诊所(HRBCC)本身并不是一项研究，而是一个研究资源，旨在从乳腺癌和卵巢癌发病率增加的家庭招募个人。来自这些个人的数据和生物谱随后被提供给研究研究。HRBCC是由国家癌症研究所资助的六个国际站点之一，该研究所包括乳腺癌研究合作家庭登记(CFRBCS)。在当地，受试者由整个地区的医生确定和转介，或从以前对高危家庭的研究中转介。登记在HRBCC的个人提供关于家族历史、医疗和人口信息以及癌症状况和治疗的数据。采集血液样本，从中获得血浆、DNA和淋巴母细胞系。受试者接受基因教育和咨询，并在适当的时候进行基因测试。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The High Risk Breast Cancer Clinic (HRBCC) is not itself a research study but is a research resource designed to recruit individuals from families with an increased frequency of breast and ovarian cancer. Data and biospecimens from these individuals are then made available for research studies. The HRBCC is one of six international sites funded by the National Cancer Institute which comprise the Cooperative Family Registry for Breast Cancer Studies (CFRBCS). Locally, subjects are identified and referred by physicians throughout the region or are referred from previous studies of at-risk families. Individuals enrolling in the HRBCC provide data about family history, medical and demographic information, and cancer status and treatment. Blood samples are obtained, from which plasma, DNA, and lymphoblast cell lines are obtained. Subjects receive genetic education and counseling, and genetic testing when appropriate.