Research Training for Medical Geneticists at Mount Sinai School of Medicine

产品说明：这是一份新的培训补助金申请，名为“西奈山医学院医学遗传学家研究培训计划”。“该计划的总体目标是培养一批医学遗传学家，使他们成为医学遗传学研究的学术带头人。研究培训的重点将是基因组学，蛋白质组学，药物遗传学，复杂性状，单基因疾病和基于分子的疗法的发展的转化研究。该计划中的所有医生科学家将获得至少两年的支持，以提供足够的时间让他们获得有意义的基础科学实验室经验，我们计划每年招募三名学员。该计划将建立在相当大的资源，包括：1）一个强有力的机构承诺，以培养医生科学家; 2）生物科学研究生院的广泛的教育产品， 基础科学，转化医学和以患者为导向的研究; 2）强大而全面的医学遗传学及其在西奈山存在了几十年的子专业培训计划，3）遗传学，基因组学和蛋白质组学的资金充足，多学科研究计划的存在;和4）该机构广泛的转化研究基础设施。西奈山医学遗传学奖学金计划的具体目标是：1）针对每个受训者的需求提供研究生级别的教学培训; 2）指导研究培训，为研究员提供竞争研究资金所需的技能; 3）在撰写资助，职业生涯建设和获得研究资金方面的实践指导，以及研究道德行为的指导。除了正式的教学课程，所有研究员将参加双周遗传学和基因组学研究系列和每年的遗传学和基因组学研究日，其中每一个都是专门为这个培训计划，为学员和教师之间的互动提供专门的会议，并促进 这群人的凝聚力。已经制定了详细的方案评价计划、培训研究员负责任地进行研究以及征聘代表性不足的少数民族候选人的计划。该计划将由执行教师委员会和外部咨询委员会提供咨询。

DESCRIPTION: This is a new application for a training grant entitled "Research Training Program for Medical Geneticists at the Mount Sinai School of Medicine." The overall goal of the program is to prepare a cadre of medical geneticists to become academic leaders in medical genetics research. The emphasis of the research training will be on translational research in genomics, proteomics, pharmacogenetics, complex traits, single gene disorders, and the development of molecular-based therapies. All physician scientists within this program will be supported for a period of at least two years to provide sufficient time for them to attain a meaningful basic science laboratory experience, and we plan to recruit three trainees per year. The program will build upon considerable resources including: 1) a strong institutional commitment to the training of physician scientists; 2) extensive educational offerings of the Graduate School of Biological Sciences in basic science, translational medicine and patient oriented research; 2) robust and comprehensive training programs in medical genetics and all its subspecialties that have existed at Mount Sinai for decades, 3) the existence of well funded, multidisciplinary research programs in genetics, genomics, and proteomics; and 4) extensive translational research infrastructure of the institution. The specific objectives of the Mount Sinai Fellowship Program in Medical Genetics are to provide: 1) graduate-level didactic training specific to the needs of each individual trainee; 2) mentored research training that will provide the fellows with the skills necessary to compete for research funding; and 3) practical instruction in grant writing, career building and obtaining research funding, and instruction in the ethical conduct of research. In addition to formal didactic courses, all fellows will participate in a bi-weekly Genetics and Genomics Research series and an annual Genetics and Genomics Research Day each of which have been specifically created for this training program to provide dedicated sessions for interaction among trainees and faculty and to promote cohesiveness of this group of fellows. Detailed plans for program evaluation, training of fellows in the responsible conduct of research and a plan for the recruitment of underrepresented minority candidates have been formulated. The program will be advised by an Executive Faculty Committee and an External Advisory Board.