SUBSTANCE ABUSE BEHAVIOR

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究的目的是比较独特的行为和生理反应，酒精和他们的协会在轻和重的社会饮酒者。 我们计划在临床前实验室研究中详细说明其目标、性能和主观酒精反应。 将在血液酒精浓度上升和下降期间获得测量结果，以便更好地了解重度酒精使用早期阶段涉及的潜在因素。 我们还计划在研究的临床前阶段后对研究参与者进行几年的随访，以检查急性酒精反应因子是否与未来的饮酒模式和酒精后果显著相关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this investigation is to compare unique behavioral and physiological responses to alcohol and their associations in light and heavy social alcohol drinkers. We plan to specify their objective, performance, and subjective alcohol response in a preclinical laboratory study. Measures will be obtained during both rising and declining blood alcohol concentrations in order to better understand potential factors involved in the earlier stages of heavy alcohol use. We also plan to follow-up on study participants for several years after the preclinical phase of the study to examine whether acute alcohol response factors are significantly associated with future drinking patterns and alcohol consequences.