Executive Team & Coordinating Core (Page 273)

执行团队和协调核心的主要目标是确保 HNRC的有效科学运作。执行团队（ET）。由中心主任组成， 联席董事、副董事和中心经理。ET提供日常领导， HNRC。ET从科学顾问委员会（每年独立）获得建议和反馈。 评估HNRC的科学和方案进展），参与者咨询委员会（反馈意见， 社区咨询委员会（来自社区提供者的反馈）， 以及内部的研究者理事会（制定政策和审查科学进展）。的 协调核心执行ET设定的优先级，并提供多项目所必需的服务 中心CC由四个单元组成：行政单元组织中心的分配 资源，协调各种中心活动，组织中心和核心的年度评估， 促进信息传播到科学界和一般社区，并确保HNRC 活动完全符合所有大学，州和联邦政策。数据管理和 信息系统股处理所有与中心有关的数据，并确保与 通过互联网访问数据资源系统的外部项目，支持国际努力， 维持网站，以便内部和外部传播信息。统计股提供 在项目开发、执行和公布结果的所有阶段提供统计服务。 参与者累积和保留（PAR）单元招募新的感兴趣的群组（例如，早期感染 病例，老年HIV+成人），维持一个信息丰富的纵向队列，管理一个潜在的研究名册， 参与者（根据具体研究的需要招募他们），并提供咨询服务。DMIS， 统计股和考绩股也参与方法制订工作。几个工作组协助和指导 核心，包括研究审查委员会（审查对中心资源的请求，并提供 讨论拟议研究/手稿的论坛）;人类受试者委员会（监测人类 受试者和IRB问题，特别是保密性）。通过这些过程和结构，ET和 协调核心确保一个真正的多学科研究中心的运作，并提供中央 协调和领导国际研究和培训工作。

The primary aim of the Executive Team and Coordinating Core is to ensure integrated, coherent, and effective scientific operations at the HNRC. The Executive Team (ET). is comprised of the Center Director, Co-Director, Associate Directors, and Center Manager. The ET provides day-to-day leadership of the HNRC. The ET receives advice and feedback from the Scientific Advisory Board (annual independent evaluation of HNRC scientific and programmatic progress), the Participant Advisory Board (feedback from participants to the Director), and the Community Advisory Board (feedback from community providers), as well as internally from the Council of Investigators (sets policy and reviews scientific progress). The Coordinating Core implements the priorities set by the ET and provides services essential to a multiproject Center. The CC is comprised of four Units: The Administrative Unit organizes the distribution of center resources, coordinates various Center activities, organizes annual evaluations of the Center and Cores, facilitates information dissemination to the scientific and general communities, and ensures that HNRC activities are fully compliant with all university, state, and federal policies. The Data Management and Information Systems Unit (DMIS) processes all Center-related data and ensures seamless interaction with external projects via an Internet-accessible data resource system, supports international efforts, and maintains the web site for internal and external information dissemination. The Statistics Unit provides statistical services during all phases of project development, implementation, and publication of findings. The Participant Accrual and Retention (PAR) Unit recruits new cohorts of interest (e.g., early infection cases, older HIV+ adults), maintains an informative longitudinal cohort, manages a roster of potential study participants (recruiting them as required for specific studies), and provides consulting services. The DMIS, Statistics, and PAR Units also engage in methods development. Several working groups assist and guide the Core, including the Research Review Committee (reviews requests for Center resources and provides a forum to discuss proposed studies/manuscripts); the Human Subjects Committee (monitors Human Subjects and IRB issues, especially confidentiality). Through these processes and structures, the ET and Coordinating Core assure the operation of a truly multidisciplinary research center and provide central coordination and leadership for international research and training efforts.