JEOL JEM-1400 Transmission Electron Microscope for the University of South Caroli

描述(由申请者提供)：本申请申请资金购买JEOL 1400透射式电子显微镜，供9名NIH资助的研究人员在南卡罗来纳大学、南卡罗来纳医科大学和弗吉尼亚理工大学Carillion校区使用。研究人员总共有19笔有效的NIH拨款，用于心血管疾病研究、阿尔茨海默氏症研究和使用替代药物来减少炎症。申请的仪器将取代已有28年历史的JEOL 200CX透射式电子显微镜，该显微镜经历了一系列维护问题，导致仪器21%的时间无法工作。申请的仪器将放置在位于医学院校园的南卡罗来纳大学仪器资源设施(IRF)。JEOL 1400具有通过图形用户界面进行远程操作的能力，这将大大加强弗吉尼亚理工大学和南卡罗来纳医科大学的研究人员的研究。IRF是一个核心的生物技术设施，拥有广泛的设备，现有的行政和研究人员，以及大学的大力支持。该提案的IRF和PI主任Robert Price博士正在与参与该提案的所有研究人员进行电子显微镜合作。

DESCRIPTION (provided by applicant): This application requests funds to purchase a JEOL 1400 transmission electron microscope for a group of 9 NIH funded investigators to be used at the University of South Carolina, the Medical University of South Carolina and the Virginia Tech Carillion campus. Together the investigators have 19 active NIH grants for research in cardiovascular disease, Alzheimer's research, and use of alternative medicines to reduce inflammation. The requested instrument will replace a 28 year old JEOL 200CX transmission electron microscope that has experienced a series of maintenance problems that have resulted in the instrument being nonfunctional 21% of the time. The requested instrument will be placed in the University of South Carolina Instrumentation Resource Facility (IRF) located on the School of Medicine campus. The JEOL 1400 has capability through the Graphical User Interface to be operated remotely which will significantly enhance the research of the investigators at Virginia Tech Carillion and the Medical University of South Carolina. The IRF is a core biotechnology facility with a wide range of equipment, an existing administrative and research staff, and strong support from the University. Dr. Robert Price, Director of the IRF and PI of this proposal, has ongoing electron microscopy collaborations with all of the investigators participating in the proposal.