Evaluating New Nicotine Standards for Cigarettes

项目总结 2021年12月9日，新西兰政府启动了无烟奥蒂亚罗亚2025行动计划， 概述了一项战略，到2025年将新西兰所有人口的吸烟率降低到5%以下。 该计划包括承诺只销售低水平的尼古丁烟熏烟草产品。最低点 尼古丁产品标准也被提议作为美国食品和药物管理局的基石 政府关于烟草和尼古丁监管的综合计划。之前的研究已经 证明当烟草使用者改用尼古丁含量很低的香烟时， 每天吸烟，吸烟暴露的依赖性和生物标志物，加上戒烟尝试和 戒烟；以及相对较少的意外后果。然而，到目前为止，还没有一个国家 实施了较低的尼古丁产品标准；因此，监管的现实影响尚未 已评估。我们建议在新西兰成年人中进行探索性序贯混合方法研究 吸食烟草香烟，以评估产品认知、对个人健康和福祉的担忧、需求 支持服务和行为意图，以回应悬而未决的强制减少所有尼古丁 烟熏烟草产品。调查还将包括包括烟草在内的广泛领域的物品 使用行为；烟草依赖；态度、信仰和规范；其他健康行为；重大健康 疾病和相关风险因素；精神健康指标；以及戒烟史。生物样本 将储存在奥克兰大学的生物储存库中，以供将来分析 烟草烟雾暴露的客观衡量标准。建议的研究重点是高风险人群。 吸烟率(对重要族裔群体进行过抽样：毛利人、太平洋岛民)，包括：1)个人 有自我报告的焦虑、抑郁和其他精神健康问题；2)年轻成年女性(18-24岁 几年)生活在新西兰的社会经济贫困地区，他们吸烟的风险要大得多 怀孕期间；以及3)报告使用重酒和/或大麻的个人。

PROJECT SUMMARY On December 9, 2021, the New Zealand Government launched the Smokefree Aotearoa 2025 Action Plan, outlining a strategy to reduce smoking prevalence to less than 5% for all populations in New Zealand by 2025. The plan includes a commitment to only having low-level nicotine smoked tobacco products for sale. A low nicotine product standard has also been proposed as a cornerstone of the United States Food and Drug Administration’s Comprehensive Plan for Tobacco and Nicotine Regulation. Previous research has demonstrated that when tobacco users switch to very low nicotine content cigarettes there is a reduction in cigarettes per day, dependence and biomarkers of smoke exposure, plus an increase in quit attempts and smoking cessation; and relatively few unintended consequences. However, to date, no country has implemented a low nicotine product standard; therefore, the real world impact of regulation has not been evaluated. We propose to conduct an exploratory sequential mixed methods study in New Zealand adults who smoke tobacco cigarettes to assess product perceptions, concerns for individual health and well-being, need for support services, and behavioral intentions in response to a pending mandated reduction of nicotine in all smoked tobacco products. The survey will also include items from a wide range of domains including tobacco use behaviors; tobacco dependence; attitudes, beliefs, and norms; other health behaviors; significant health conditions and associated risk factors; mental health indicators; and smoking cessation history. Biosamples will be banked in a biorepository located at the University of Auckland for future analysis of changes in objective measures of exposure to tobacco smoke. The proposed research focuses on populations with high smoking prevalence (oversampling important ethnic groups: Maori, Pacific Islanders), including: 1) Individuals with self-reported anxiety, depression and other mental health concerns; 2) Young adult women (age 18-24 years) living in socioeconomically deprived areas of New Zealand who are at a much greater risk of smoking during pregnancy; and 3) Individuals who report heavy alcohol and/or cannabis use.