NEIBank: Est Analysis And Bioinformatics For Ocular Genomics

许多人的眼睛（和耳朵）组织和重要的动物模型现在已经被分析。此外，NEIBank的合作增加了其他感觉组织，耳朵和味蕾的数据。最近增加的眼睛包括人类视神经和人类翼状胬肉。该DNA资源已用于创建具有13，000个非冗余人眼表达序列和6500个来自小鼠眼睛的序列的cDNA微阵列。这些被用于分析人类细胞反应和转基因小鼠模型。 眼睛研究信息学工具的一个强大补充是EyeBrowse，这是一个专门用于眼睛表达基因的基因组浏览器，与CIT合作生产。http://eyebrowse.cit.nih.gov/genome/. 主要增加的是人类眼病基因的注释数据库和基因组的候选眼病区域的数据库，其显示在EyeBrowse中，具有所有已知的人眼来源的cDNA和SAGE数据，指示眼睛特异性的表达谱。

Many human eye (and also ear) tissues and those of important animal models have now been analyzed. In addition NEIBank collaborations have added data on other sensory tissues, ear and taste bud. Recent eye additions include human optic nerve and human pterygium. This DNA resource has been used to create cDNA microarrays with 13,000 non-redundant human eye expressed sequences and 6500 sequences from mouse eye. These are being used in analysis of human cellular responses and genetically modified mouse models. A powerful addition to the informatics tools for eye research is EyeBrowse, a dedicated genome browser for eye-expressed genes, produced in collaboration with CIT. http://eyebrowse.cit.nih.gov/genome/. Major additions are an annotated database of human eye disease genes and databases of candidate eye disease regions of the genome which are displayed in EyeBrowse with all known human eye-derived cDNAs and SAGE data, indicating expression profiles specific to eye.