Oregon Clinical and Translational Science Institute

___ 俄勒冈州的生物医学研究机构非常出色，并准备在 临床/翻译研究。我们建议成立俄勒冈州临床和转化科学研究所 （OCTSI）。OCTSI将从根本上改变生物医学研究， 临床/翻译研究。它将利用现有的优势，消除阻碍步伐的障碍， 研究的增长。OCTSI的核心是俄勒冈州健康与科学之间的强大伙伴关系 大学（OHSU）和凯撒永久健康研究中心（KPCHR），汇集了一个 强大的生物医学研究型大学和创新的实践为基础的研究中心与 患者群体庞大。此次合作为整个频谱的扩展提供了独特的机会 人类研究的基础，并为人类健康的重大进步奠定了基础。 俄勒冈州的临床和翻译研究的转变通过以下方式得到加强： 对OCTSI的强有力的机构支持，表现在重大的行政改革以及 承诺提供大量财政和空间资源 <$在OHSU和KPCHR的学术院系，完全支持OCTSI倡议和发展的一个 强大的多学科OCTSI领导团队 整合资源，形成临床/转化研究的协调基础设施 与社区的紧密联系以及该地区对人类研究议程的参与 我们确定了OCTSI的三个主要目标，并提出了深远，明确和可行的目标 方法来实现它们。我们将1）创建一个学术之家（OCTSI）专门致力于 临床/转化研究的学科，2）培养一个新的干部，训练有素，跨学科 研究人员通过强大的，多样化的教育课程，3）创建一个“研究共享”-一个 核心研究工具的协调基础设施，大大扩大了研究机会，并提供了一个 统一的、有效的手段。 有特别的机会，以加快在儿科和儿童健康，社区为基础的进展 研究和人类遗传学。

___ Biomedical research institutions in Oregon are outstanding, and are prepared for a major expansion in clinical/translational investigation. We propose to form the Oregon Clinical and Translational Science Institute (OCTSI). The OCTSI will fundamentally change biomedical researchto create a vibrant academichome for clinical/translational investigation. It will leverage existing strengths and remove barriers to the pace and growth of research. At the heart of the OCTSI is a robust partnership between Oregon Health & Science University (OHSU) and Kaiser Permanente's Center for Health Research (KPCHR) that brings together a strong biomedical research university and an innovative practice-based research center associatedwith a large patient population. The collaboration provides unique opportunities for expansion across the spectrum of human investigation, and sets the stage for major advances in human health. Transformation of clinical and translatlonal research in Oregon is enhanced by: ¿ Robust institutional support for the OCTSI, manifest by significant administrative change as well as the commitment of substantial financial and space resources ¿ Academic faculties at OHSU and KPCHR that fully support the OCTSI initiative and the development of a strong, multidisciplinary OCTSI leadership team ¿ Merging of resourcesto form a coordinated infrastructure for clinical/translational research ¿ Strong ties to the community and the involvement of the region in the human researchagenda We have identified three major goals for the OCTSI, and propose far-reaching, explicit andfeasible approaches to achieve them. We will 1) Create an academic home (the OCTSI) specifically devoted to the discipline of clinical/translational research, 2) Nurture a new cadre of highly-trained, interdisciplinary investigators through a strong, diverse educational curriculum, 3) Create a "Research Commons"- a coordinated infrastructure of core research tools that greatly expands research opportunities and provides a unified, effective means for their access. There are particular opportunities to accelerate progress in pediatric and child health, community based research, and human genetics.