3T MR scanner for imaging from mouse to human

描述(由申请人提供)：这项建议的目的是促进购买3T核磁共振扫描仪，用于康奈尔大学的基础和应用研究。这款3T扫描仪将是康奈尔·伊萨卡校区的第一台核磁共振研究仪器，提供从老鼠到人类的高信噪比、成像速度以及空间和光谱分辨率的成像能力。这款专门用于研究的扫描仪将弥补NIH资助的生物医学和神经科学项目在校园内严重缺乏磁共振成像的问题。此外，它还将维持、加强和支持康奈尔大学的高质量生物医学研究。3T核磁共振扫描仪将是全大学范围内的资源，作为核磁共振核心设施安置在康奈尔·伊萨卡大学人类生态学院内。已经为3T核磁共振扫描仪的运作分配了空间和大量基础设施。购买、场地准备和安装3T核磁共振扫描仪的总成本约为280万美元。除了从这项提案中申请的200万美元之外，该大学(负责研究的副教务长、人类生态学院、兽医学院、工程学院、文理学院和生物医学工程系)已承诺提供资金和资源，以支付与此次购买相关的剩余费用，以及最初为期两年的运作。康奈尔大学核磁共振核心设施的使命是促进非侵入性成像技术的开发和在广泛的医学研究学科中的协同应用。核磁共振核心的组织、人员配置、设备采购和业务资金都是为了确保这项任务的成功。目前，有22个NIH正在进行的项目(17个R01、2个R21、1个R03和2个合同)大量使用磁共振成像。此外，这一核磁共振核心基金将增强/启用20项待决的NIH拨款提案。这台要求的3T磁共振扫描仪将提供从老鼠到人类成像所需的平衡技术。它被纳入校园范围的核心研究设施，对于成功开展和扩大NIH资助的我们机构的尖端成像研究项目至关重要。 公共卫生相关性：

DESCRIPTION (provided by applicant): The purpose of this proposal is to facilitate the purchase of a 3T MRI scanner for basic and applied research at Cornell University. This 3T scanner will be the first MRI research instrument at the Cornell Ithaca campus, providing capabilities for imaging from mouse to human with high signal-to-noise ratio, imaging speed, and spatial and spectral resolution. This research-dedicated scanner will remedy the critical lack of MRI access for biomedical and neuroscience NIH-funded projects on campus. Moreover, it will maintain, enhance and enable high quality biomedical research at Cornell University. The 3T MRI scanner will be a University-wide resource housed as an MRI Core Facility within the College of Human Ecology, Cornell Ithaca campus. Space and substantial infrastructure for operations for the 3T MRI scanner have been allocated. The total cost for purchasing, site preparation and installation of the 3T MRI scanner is approximately $2.8M. In addition to the requested $2M from this proposal, the University (Vice Provost for Research, College of Human Ecology, College of Veterinary Medicine, College of Engineering, College of Arts and Sciences, and Department of Biomedical Engineering) has committed the funds and resources to cover the remaining costs associated with this purchase, as well as the initial two-year operation. The mission of Cornell University's MRI Core Facility is to promote the development and synergistic application of non-invasive imaging techniques to a broad range of medical research disciplines. The organization, staffing, equipment procurement, and operational funding of the MRI Core are all designed to assure the success of this mission. Presently, there are 22 active NIH projects (17 R01s, 2 R21s, 1 R03, and 2 contracts) that make substantial use of magnetic resonance imaging. Additionally, 20 pending NIH grant proposals will be enhanced/enabled by this MRI Core Facility. This requested 3T MRI scanner will provide a balanced technology needed for imaging from mouse to human. Its incorporation into a campus-wide core research facility is essential for successfully conducting and expanding NIH-funded cutting-edge imaging research programs at our institution. PUBLIC HEALTH RELEVANCE: