Postdoctoral Training in Cardiovascular Disease

描述(由申请人提供)： 本申请要求为心血管疾病博士后培训计划的第二次竞争性续签提供资金。最初，该培训计划是为外科住院医生设计的，为心血管科学领域的研究生涯做准备。在第一次竞争续签申请中，重点扩大到包括那些接受过心脏病学专科培训、希望致力于心血管科学基础方面事业的个人。在第二次竞争更新中，重点将继续放在接受外科和心脏病学次级专业培训的个人身上，使他们能够参加2-3年的强化研究培训，从分子生物学到结果/临床研究等广泛的研究领域进行选择。哥伦比亚大学医学中心的心血管科学培训计划旨在促进和确保外科和心脏病专家、内科医生和科学家的发展，旨在使这些年轻的研究人员能够在未来启动基于实验室的心血管科学研究计划。经过两个资金周期，很明显，该计划在完成这一使命方面非常成功，培训外科住院医师和心脏病学研究员基本研究方法和技术，翻译和流行病学研究，以及导致多篇出版物和内科科学家发展的结果研究，他们中的大多数已经或将继续从事学术生涯。在这第二次的竞争更新中，我们将继续在基础调查方面保持卓越。每个子领域的范围扩大了，基因治疗、细胞信号和免疫学、翻译和结果研究等领域也扩大了，血管生物学和离子通道研究的计划也扩大了。两个新的项目，成果研究和临床科学，为申请者提供了更多的机会，在一流的设施和优秀的导师下从事尖端的翻译研究。利用哥伦比亚大学医学中心的基础科学家和临床研究人员的非凡深度，这一培训计划旨在培训具有先进研究技术的内科科学家，同时通过一系列核心讲座和教学计划提供个人关注，旨在对具有优秀少数民族和/或女性代表的内科医生和外科医生进行研究培训。(摘要结束)

DESCRIPTION (provided by applicant): This application requests funding for the second competitive renewal of a postdoctoral training program in cardiovascular diseases. Initially the training program was designed for surgical residents, to prepare for an investigative career in cardiovascular sciences. In the first competitive renewal application, the focus was broadened to include those individuals with cardiology subspeciality training, who wished to dedicate themselves to careers in fundamental aspects of cardiovascular science. In this second competitive renewal, the focus will continue to be on individuals with surgical and cardiology subspeciality training, enabling them to engage in an intensive 2-3 year research training, choosing from broad group of investigative areas, ranging from molecular biology to outcomes/clinical research. The training program in Cardiovascular Sciences at Columbia University Medical Center was conceived to enhance and ensure the development of surgical and cardiologist physician-scientists and was designed to enable such young investigators to initiate a laboratory-based research program in Cardiovascular Sciences in the future. After two funding cycles, it is evident that the program is extremely successful in fulfilling this mission, training surgical residents and cardiology fellows in basic research methodology and techniques, translational and epidemiologic research, and outcome studies leading to multiple publications and the development of physician-scientists, most of whom have, or will be going on, to academic careers. In this second competitive renewal, we will continue the excellence in basic investigation. The scope within each sub-area has been enlarged, and such areas as gene therapy, cell signaling and immunology, translational and outcome research have been expanded, as have the the programs in vascular biology and ion channel research. Two new programs, Outcomes Research and Clinical Sciences, offer the applicant even greater opportunities to engage in cutting-edge translational research in excellent facilities and with outstanding mentors. Utilizing the remarkable depth of basic scientists and clinical investigators within Columbia University Medical Center, this training program is powered to train physician-scientists with advanced research techniques, yet provide individual attention through a series of core lectures and didactic program geared towards the research training of physicians and surgeons with an excellent representation of minorities and/or women. (End of Abstract)