MBRS SCORE at San Francisco State University

这项竞争更新申请的总体目标是支持我们的MBRS SCORE计划，以进一步推动旧金山州立大学（SFSU）的长期目标，提高其从事生物医学研究的教师的生产力和水平，并显着增加从事和追求生物医学事业的少数民族教师和学生的数量。我们提议的SCORE计划的具体目标是提高：(1)参与的教师在同行评议期刊上发表原创研究的速度和质量；(2)参与院校在资助期内提交及资助重大资助申请（包括r01级申请），以支持生物医学研究；(3)与会教师在国内和国际会议上展示研究成果；(4)旧金山州立大学聘用和保留代表性不足的少数族裔教师；(5)旧金山州立大学生物医学研究基础设施的范围和有效性；(6)在SCORE研究项目中接受培训的少数族裔学生人数。我们的项目旨在保持我们持续的高级pi的研究竞争力，因为他们坚持提交主要的R01级拨款申请，以过渡到SCORE资助的目标，并发展我们中级pi的竞争力，以提交高质量的R01申请，以及发展我们初级和最新的生物医学学院的研究能力。本申请书中提出的25个研究项目中，有9个来自乌尔班大学的教职员工。

The overall goal of this competitive renewal application for support of our MBRS SCORE program is to further San Francisco State University's (SFSU's) long-term objective to increase the productivity and caliber of its faculty conducting biomedical research and to significantly increase the number of minority faculty and students engaged in and pursuing biomedical careers. The specific goals of our proposed SCORE program are to increase: (1) the rate and quality of publication of original research by participating faculty in peer-reviewed journals; (2) the submission and funding of major grant applications, including R01-level applications, supporting biomedical research by participating faculty during the award period; (3) the presentation of research results by participating faculty at national and international meetings; (4) the hiring and retention of underrepresented minority faculty at SFSU; (5) the scope and effectiveness of the biomedical research infrastructure at SFSU; and (6) the number of underrepresented minority students trained in SCORE research programs. Our program is designed to maintain the research competitiveness of our continuing senior PIs as they persist in submitting major R01-level grant applications with the goal of transitioning off SCORE funding and to develop the competitiveness of our intermediate level PIs to the point of submitting quality R01 applications, as well as to develop the research capacity of both our junior and newest biomedical faculty. Nine of the 25 research projects proposed in this application are from URM faculty members. Together, all 25 projects will provide our students with an unprecedented breadth of research and training opportunities in developmental biology, enzymology, immunology, neurophysiology, microbiology, virology, plant molecular biology, organic chemistry, physical chemistry, and mathematical and computational modeling in experimental models that range from yeast, weeds, worms, flies, crabs, fish, frogs, chicks and mice. The program director and assistant program director will advise and monitor the progress of all SCORE research projects and administer the program in consultation with the MBRS Advisory Committee. An External Scientific Advisory Committee will advise individual investigators on the scientific focus and progress of research projects and advise the program directors on measures to improve infrastructure. A comprehensive evaluation of the SCORE program will continue to be provided by external evaluators from SFSU's Public Research Institute.