Core Grant for Vision Research

描述(由申请者提供)：纽约大学神经科学中心是研究视觉功能方面的首选场所。该中心的18名研究人员通过继续发放核心补助金，请求为他们的视力研究提供支持。他们在视觉和视觉引导行为的神经和行为基础上的研究兴趣将他们联系在一起。拟议的核心将由四个模块组成，每个模块都将有利于项目教员代表的研究领域的研究：1.视觉显示模块，它将为开发最先进的软件提供支持，以产生各种视觉刺激，用于心理物理、神经生理和大脑实验。2.设计和制造模块，将提供专业知识来设计和制造新的电子和机械设备，如视皮层多电极记录所需的绳索，非侵入性眼动记录方法，以及用于行为和眼球实验的接口设备。3.神经解剖学和分子生物学模块，它将为光和EM水平的神经解剖材料的处理提供专家支持，为组织材料中电生理记录位置的分析和定位提供专家支持，并为创建转基因病毒以在实验上修改神经元功能提供专家支持。4.功能成像模块，它将为西门子核磁共振扫描仪和脑成像中心的相关设备的用户提供硬件和软件服务支持，使核心研究人员能够获得用于人类和动物研究的功能和结构成像能力。

DESCRIPTION (provided by applicant): The Center for Neural Science at New York University is a premier site for research on functional aspects of vision. Eighteen investigators from the Center request support for their vision research through continuation of a Core Grant. They are bound together by their research Interests In the neural and behavioral bases of vision and visually guided behavior. The proposed Core will comprise of four modules, each of which will benefit research in the research areas represented by program faculty: 1. A Visual Displays Module which will provide support for the development of state-of-the-art software for the generation of a wide variety of visual stimuli for psychophysical, neurophysiological, and brain experiments. 2. A Design and Fabrication Module which will provide expertise to design and build novel electronic and mechanical devices such as theose required for multielectrode recording in the visual cortex, noninvasive methods of eye movement recording, and Interface devices for behavioral and blloglcal experiments. 3. A Neuroanatomy and Molecular Biology Module which will provide expert support for the processing of neuroanatomlcal material at both the light and EM level, for the analysis and localization of electrophysiological recording sites In histological material, and for the creation of transgene-containing viruses to modify neuronal funtlon experimentally. 4. A Functional Imaging Module which will provide support for hardware and software services for users of the Siemens MRI scanner and associated devices In the Center for Brain Imaging, giving access for Core researchers to functional and structural Imaging capabilities for human and animal research.