Neuroimaging Sciences Training Program

描述(由申请人提供)：这项新的机构拨款要求为四个博士后职位提供资金，用于神经成像方面的培训和研究。本课程将重点介绍两大类神经成像：放射性示踪剂和核磁共振。具体的成像方法由以下首字母缩写描述：PET(正电子发射断层扫描)、MRI(磁共振成像)、fMRI(功能磁共振成像)和MRS(磁共振波谱)。这些成像方法为神经成像在诊断、治疗和了解主要神经精神疾病的病理生理学方面的临床应用提供了真正的希望。然而，这些新的方法通常来自复杂的、多学科的科学，从而为它们在医疗实践中的进一步发展和应用创造了一个具有挑战性的信息障碍。拟议计划的目的如下：-为博士后研究员提供正式课程培训，重点是成像和临床研究方法，并指导他们的基础多学科科学。-为研究员提供辅导培训，以应用这些新方法，促进我们对大脑在健康、药物滥用和其他精神疾病中的功能的跨学科理解。-为研究员提供成像应用和方法学方面的综合研究体验。所有研究员将被要求在培训期间完成至少一个研究项目和一个方法论导师。通过将这一计划组织成两个规模大致相同的互动轨道：方法学和应用，将加强方法学和成像应用方面的培训的整合。我们预计，方法论课程的大多数研究员将拥有博士学位，而应用课程的研究员将拥有博士学位，主要是医学博士学位。每个研究员将有一名初级和二级教师导师代表这两个轨道。

DESCRIPTION (provided by applicant): This new institutional grant requests funds for four postdoctoral positions for training and research in neuroimaging. Two general classes of neuroimaging will be emphasized: radiotracer and nuclear magnetic resonance. The specific imaging methods are described by the following acronyms: PET (positron emission tomography, MRI (magnetic resonance imaging), fMRI (functional magnetic resonance imaging), and MRS (magnetic resonance spectroscopy). These imaging methodologies offer real promise for the expanded clinical utility of neuroimaging in the diagnosis, treatment, and understanding of the pathophysiology of major neuropsychiatric disorders. However, these new methodologies typically derive from complex, multidisciplinary sciences, which thereby create a challenging information barrier to their further development and application in medical practice. The purposes of the proposed program are the following: - Provide formal course training to postdoctoral fellows, with an emphasis on imaging and clinical research methodology, and instruction in their underlying multidisciplinary sciences. - Provide mentored training for fellows to apply these new methods to the interdisciplinary advance of our understanding of the function of the brain in health, substance abuse, and other psychiatric diseases. - Provide an integrated research experience for the fellows in both imaging applications and methodology. All fellows will be expected to complete at least one research project with an applications and one with a methodology mentor during their training period. The integration of training in methodology and imaging applications will be enhanced by the organization of this program as two interactive tracks of approximately equal size: Methodology and Application. We expect that the majority of fellows in the Methodology track will have Ph.D. degrees, and those in the Application track, primarily M.D. degrees. Each fellow will have a primary and secondary faculty mentor to represent the two tracks.