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Molecular, Cellular, and Animal Models Core

Molecular, Cellular, and Animal Models Core
分子、细胞和动物模型核心
批准号：
9077588
负责人：
Anton M Bennett
金额：
$26.73万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
项目状态：
未结题
起止时间：
2001-05-01 至
来源：
https://reporter.nih.gov/project-details/9077588
关键词：
AdenovirusesAnimal ModelBreedingCalciumCell modelCellular biologyChronicCommunitiesDevelopmentGenerationsGenotypeGoalsHepatocyteHuman ResourcesIndividualInstitutionLaboratoriesLiverLiver diseasesMaintenanceMitogen-Activated Protein KinasesMolecular BiologyMolecular ModelsMusPhosphoric Monoester HydrolasesPlasmid Cloning VectorPlasmidsProtocols documentationReagentRegulationServicesSignal TransductionSmall Interfering RNASourceStandardizationSubfamily lentivirinaeTechniquesabstractingliver injurymolecular modelingmouse modelprogramsrepositoryresponse

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英文摘要
Summary/Abstract: The Molecular, Cellular and Animal Model Core (Core B) will provide reagents to assist in the study of calcium, InsP3R, MAP kinases/phosphatases and OGT signaling in the liver. The core will assist in the development and characterization of expression plasmids, siRNA and lentiviral constructs as requested for use in the individual projects. The core will serve as a central repository for all the reagents generated by the four projects and assist in their distribution to other laboratories outside of the institution. The core will include dedicated personnel and will be located within the Director's laboratory.
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Dual-specificity phosphatase action in muscle disease
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