Cancer Biology Training Program

摘要 这一竞争性的续期申请要求露丝·基尔施斯坦国家基金会提供第二个五年的支持。 研究服务奖（T32）为我们的“癌症生物学培训计划”设在得克萨斯大学 健康科学中心在圣安东尼奥（UTHSCSA），西班牙裔服务机构。巨蟹座的目标 生物学培训计划是教育和培训下一代癌症研究人员（前和 博士后培训生），以满足对癌症生物学多方面培训的科学家日益增长的需求。 自2011年8月T32奖开始以来，所有实习生职位（1名博士前和3名博士后） 不断被填满。因此，到目前为止，已有四名博士前学生和七名博士后研究员 被任命为T32受训人员，其中三人来自生物医学领域代表性不足的人群， 以理工科为重展望未来，我们要求资金支持相同数量的博士前（1）和博士后（3） 实习生学员将根据他们的学术成就和对癌症研究的奉献精神被选中。 培训项目有28名教师导师（19名正教授，6名副教授，3名助理 教授; 22名男性和6名女性）来自8个部门，他们在研究生院享有完全的教师特权 以及NCI指定的癌症中心、癌症治疗和研究中心（CTRC），并与 多样化的专业知识，为学员提供深度和广度的研究机会。导师们， 分享几个合作项目，非常互动，有很好的资助研究记录（平均 本年度每位导师的直接成本> 50万美元）以及指导博士前和博士后 伙计们培训计划包括博士前和博士后学员谁是任命的一段时间， 两到三年培训课程（包括两门癌症生物学核心课程，一本癌症生物学杂志 俱乐部和药物开发系列讲座）强调基本和转化方法，以提供 为博士前和博士后学员提供广泛的当代癌症主题的优秀培训 生物学，并给他们一个坚实的背景，在肿瘤学必要的研究，他们的成功都近， 长期和长期。该课程最近因采用新的教学法而得到振兴， 生物信息学，也强调培训科学交流的机会，以提高口语和 写作技巧。该培训计划利用校园内不断增长的基础和临床研究机会 和积极的研讨会系列，特别是在CTRC-唯一的NCI指定的癌症中心在南德克萨斯州， 从PI的系主任到大学校长的强有力的全面机构支持。这 我们机构唯一一个由NCI资助的T32培训项目是独一无二的，它将培养一批即将到来的多元化干部。 癌症研究人员，因为大量代表性不足的少数民族（URM）学员被吸引到我们的 该计划使这成为一个独特的机会，以丰富未来独立调查人员的多样性 从事癌症研究

Abstract This competing renewal application requests a second five-year support by the Ruth Kirschstein National Research Service Award (T32) for our “Cancer Biology Training Program” based at the University of Texas Health Science Center at San Antonio (UTHSCSA), a Hispanic-Serving Institution. The goal of the Cancer Biology Training Program is to educate and train the next generation of cancer researchers (pre- and postdoctoral trainees) to meet the growing demands for scientists trained in multiple facets of cancer biology. Since the start of the T32 award in August 2011, all trainee positions (1 predoctoral and 3 postdoctoral) have continuously been filled. As a result, to date four predoctoral students and seven postdoctoral fellows have been appointed as T32 trainees including three from populations that are underrepresented in the biomedical sciences. Going forward, we request funds to support the same number of predoctoral (1) and postdoctoral (3) trainees. Trainees will be selected for their academic achievements and their dedication to cancer research. The training program has 28 faculty mentors (19 full professors, 6 associate professors, and 3 assistant professors; 22 men and 6 women) from 8 departments who have full faculty privileges in the Graduate School as well as in the NCI-designated Cancer Center, the Cancer Therapy and Research Center (CTRC), and with diverse expertise that provides depth and breadth of research opportunities for trainees. The mentors, who share several collaborative projects and are very interactive, have a strong record of funded research (average direct costs >$500K per mentor in the current year) as well as in mentoring predoctoral and postdoctoral fellows. The Training Program includes predoctoral and postdoctoral trainees who are appointed for a period of two to three years. The training curriculum (including two cancer biology core courses, a cancer biology journal club, and a drug development lecture series) stresses both basic and translational approaches to provide outstanding training for predoctoral and postdoctoral trainees in broad range of contemporary topics in cancer biology and to give them a solid background in oncology necessary for their success in research both near- term and long-term. The curriculum, which has recently been revitalized with introduction of new didactics in bioinformatics, also emphasizes training in scientific communication with opportunities to improve both oral and written skills. The training program leverages the growing basic and clinical research opportunities on campus and active seminar series, especially at CTRC – the only NCI-designated Cancer Center in South Texas, and strong across-the-board institutional support from the PI's department chair to the university president. This sole NCI-funded T32 Training Program at our institution is uniquely poised to train a diverse cadre of upcoming cancer researchers because a large number of underrepresented minority (URM) trainees are attracted to our program making this a unique opportunity to enrich the diversity in the pool of future independent investigators working in cancer research.