Graduate Training Program in Cancer Biology - Renewal 01

描述(由申请者提供)：芝加哥大学的癌症生物学培训项目(CBTP)是一个多学科项目，其核心任务是在癌症研究的不同领域培训研究生和博士后研究人员，包括但不限于癌症生物学的基本分子机制、系统方法、重新启动发展项目和模式生物的使用、器官部位生物学、癌症治疗学和癌症种群遗传学。此外，我们的受训人员在假设建立和检验、科学努力的伦理道德、教学技能以及对他们的工作如何为人类福祉和社会疾病管理做出贡献的理解方面获得了坚实的基础。在过去5年的培训资助中，我们的癌症生物学项目已经牢固地确立了自己作为一个有效和充满活力的培训项目的地位，培训了下一代癌症生物学家，以应对社会癌症发病率上升带来的医疗保健挑战。我们的43名教师培训师一直保持着出色的发表记录，并获得了许多享有盛誉的荣誉。尽管资金环境充满挑战，但与2008年相比，我们的教职员工在2013年增加了对他们研究的直接资助。强大的机构支持也使我们能够招聘有才华的新教员，他们的专业知识增加了我们的学员在令人兴奋的癌症生物学和科学新领域的研究机会。值得注意的是，我们继续收到越来越多的合格申请者参加我们的计划。我们还感到高兴的是，我们能够显著增加招募到我们计划中的代表性不足的少数族裔的数量，这些受训人员是我们最具活力的学员之一。在过去的五年里，我们对我们的计划进行了严格的评估，以进一步改进我们的课程，以满足这十年来癌症研究不断变化的面貌。特别是，我们开发了课程的新方面，改变了正规课程的要求，并为受训人员提供了个人发展机会方面的进展。该计划也得到了新的领导，Kay Macleod博士接替Geof Greene博士担任这项培训拨款的主任。与该项目之前的所有领导层变动一样，由于麦克劳德博士在过去5年里与格林博士密切合作，格林博士仍是领导层结构的一部分，因此连续性仍然存在。重要的是，麦克劳德博士带来了新的活力和想法，使该项目在培训目标上保持有目的和目标导向。总而言之，凭借我们的师资培训专家团队和年轻学员的才华横溢的团队，加上不断改善的课程和培训环境，我们的项目在学员生产率和职业生涯成果方面取得了极大的成功。鉴于我们计划的这些优势，以及我们持续招募更多合格、杰出的学员的能力，我们建议该计划需要并值得在此次培训拨款续签中保留博士后(8名)和博士后(3名)的名额。

DESCRIPTION (provided by applicant): The Cancer Biology Training Program (CBTP) at the University of Chicago is a multi-disciplinary program whose core mission is to train graduate students and post-doctoral researchers in different areas of cancer research, including but not limited to fundamental molecular mechanisms in cancer biology, systems approaches, reactivation of developmental programs and use of model organisms, organ site biology, cancer therapeutics and cancer population genetics. In addition, our trainees receive robust grounding in hypothesis building and testing, the ethics of scientific endeavor, teaching skills and an understanding of how their work contributes to human well-being and disease management in society. Over the past 5 years of training grant support, our cancer biology program has firmly established itself as an effective and vibrant training program, training the next generation of cancer biologists needed to meet the health cares challenges arising from increasing cancer incidence in society. Our 43 faculty trainers have maintained an outstanding publication record and have been recognized by many prestigious honors. Despite a challenging funding climate, our faculty have increased direct funding of their research in 2013 compared to 2008. Strong institutional support has also allowed us to recruit talented new faculty whose expertise has increased the research opportunities for our trainees in exciting new areas of cancer biology and science. Significantly, we continue to receive an ever-increasing number of qualified applicants to our program. We are also pleased that we have been able to make significant increases in numbers of under-represented minorities recruited to our program, and these trainees are amongst our most dynamic. We have evaluated our program rigorously over the past 5 years to improve yet further our curriculum to meet the changing face of cancer research in this decade. In particular, we have developed new aspects of the curriculum, with altered demands in formal coursework, as well as introduced advances in personal development opportunities for trainees. The program has also come under new leadership with Dr. Kay Macleod taking over from Dr. Geof Greene as Director of this training grant. As with all previous leadership changes to the program, continuity remains thanks to Dr. Macleod having worked closely with Dr. Greene in the past 5 years and Dr. Greene remaining part of the leadership structure. Importantly, Dr. Macleod brings renewed energy and ideas to keep the program purposeful and goal-oriented in its training objectives. In summary, with our expert body of faculty trainers and talented group of young trainees, plus a constantly improving curriculum and training environment, our program has been highly successful in terms of trainee productivity and career outcomes. Given these strength of our program and our sustained ability to recruit increased numbers of qualified, outstanding trainees, we suggest that the program needs and merits retaining the number of pre-doctoral (8) and post-doctoral (3) slots in this training grant renewal.