Research Fellowship
Research Fellowship
批准号:
nhmrc : 1027369
负责人:
Prof David Fairlie
金额:
$55.8万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
关键词:
中文摘要
这项研究汇集了我在药物化学,生物化学,药理学和病毒学方面的专业知识,以设计和开发新的化合物,我们可以用来询问和调节导致疾病的人类和病毒蛋白质。与21世纪主要健康负担(如炎症、感染和代谢疾病、癌症、疼痛和病毒感染)相关的蛋白质、细胞和动物研究将为疾病发展和药物作用机制提供重要的新信息。
英文摘要
This research draws together my expertise in medicinal chemistry, biochemistry, pharmacology and virology to design and develop new compounds that we can use to interrogate and regulate human and viral proteins that cause disease. Protein, cell and animal studies relevant to major 21st century health burdens (such as inflammatory, infectious and metabolic diseases, cancer, pain and viral infections) will provide important new information on mechanisms of disease development and drug action.
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会议论文
Super-resolution platform to accelerate biological and molecular research
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批准号:LE240100134
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$53.09万
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财政年份:2024
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负责人:Prof David Fairlie
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依托单位:
Compressing small peptides for cell absorption
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批准号:DP180103244
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项目类别:Discovery Projects
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资助金额:$40.43万
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财政年份:2018
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负责人:Prof David Fairlie
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依托单位:
Combating infectious diseases by harnessing macrophage functions
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批准号:nhmrc : GNT1125316
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项目类别:Project Grants
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资助金额:$68.82万
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财政年份:2017
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负责人:Prof David Fairlie
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依托单位:
Modulating Protein-Protein Interactions In Disease
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批准号:nhmrc : GNT1117017
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项目类别:Research Fellowships
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资助金额:$86.39万
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财政年份:2017
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负责人:Prof David Fairlie
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依托单位:
Combating infectious diseases by harnessing macrophage functions
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批准号:nhmrc : 1125316
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项目类别:Project Grants
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资助金额:$46.96万
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财政年份:2017
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负责人:Prof David Fairlie
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依托单位:
Modulating Protein-Protein Interactions In Disease
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批准号:nhmrc : 1117017
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项目类别:Research Fellowships
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资助金额:$59.07万
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财政年份:2017
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负责人:Prof David Fairlie
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依托单位:
Engineering peptides into superglues selective for target proteins
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批准号:DP160104442
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项目类别:Discovery Projects
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资助金额:$37.48万
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财政年份:2016
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负责人:Prof David Fairlie
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依托单位:
Engineering Cyclic Peptides For Oral Bioavailability
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批准号:DP150104609
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项目类别:Discovery Projects
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资助金额:$34.7万
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财政年份:2015
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负责人:Prof David Fairlie
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依托单位:
Development of antimalarial histone deacetylase inhibitors
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批准号:nhmrc : GNT1093378
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项目类别:Development Grants
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资助金额:$55.68万
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财政年份:2015
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负责人:Prof David Fairlie
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依托单位:
Development of antimalarial histone deacetylase inhibitors
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批准号:nhmrc : 1093378
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项目类别:Development Grants
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资助金额:$38.25万
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财政年份:2015
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负责人:Prof David Fairlie
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依托单位:
Downsizing A Human Protein To Modulate Inflammatory Diseases
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批准号:nhmrc : 1084018
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项目类别:Project Grants
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资助金额:$34.46万
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财政年份:2015
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负责人:Prof David Fairlie
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依托单位:
Anti-Parasitic Drug Discovery in Epigenetics
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批准号:nhmrc : 1074016
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项目类别:Targeted Calls
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资助金额:$18.15万
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财政年份:2014
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负责人:Prof David Fairlie
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依托单位:
Downsizing proteins to equipotent small molecules that activate cells
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批准号:DP130100629
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项目类别:Discovery Projects
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资助金额:$34.11万
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财政年份:2013
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负责人:Prof David Fairlie
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依托单位:
Capturing New Drugs That Selectively Modulate PAR2 Signaling Pathways
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批准号:nhmrc : 1047759
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项目类别:Project Grants
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资助金额:$31.28万
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财政年份:2013
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负责人:Prof David Fairlie
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依托单位:
Small Molecule Modulators of Complement in Metabolism and Obesity
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批准号:nhmrc : 1028423
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项目类别:Project Grants
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资助金额:$45.53万
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财政年份:2012
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负责人:Prof David Fairlie
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依托单位:
Flaviviral proteases as viable targets for antiinfective drugs
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批准号:nhmrc : 1025883
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项目类别:Project Grants
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资助金额:$41.39万
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财政年份:2012
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负责人:Prof David Fairlie
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依托单位:
Profiling global inflammatory signatures for GPCRs in human macrophages
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批准号:nhmrc : 1030169
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项目类别:Project Grants
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资助金额:$45.86万
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财政年份:2012
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负责人:Prof David Fairlie
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依托单位:
Protein And Peptide Alpha Turns
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批准号:DP1096290
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项目类别:Discovery Projects
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资助金额:$25.08万
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财政年份:2010
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负责人:Prof David Fairlie
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依托单位:
Protease Activated Receptor 2 Antagonist In Inflammatory Disease
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批准号:nhmrc : 1000745
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项目类别:NHMRC Development Grants
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资助金额:$41.43万
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财政年份:2010
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负责人:Prof David Fairlie
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依托单位:
Common hot spots in protein-activated GPCRs enable discovery of new ligands for mapping of G-protein signalling pathways
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批准号:DP1093245
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项目类别:Discovery Projects
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资助金额:$62.7万
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财政年份:2010
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负责人:Prof David Fairlie
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依托单位:
海外基金