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The role of meninges in midbrain dopamine development

The role of meninges in midbrain dopamine development
脑膜在中脑多巴胺发育中的作用
批准号:
nhmrc : 1079762
负责人:
A/Pr Clare Parish
金额:
$25.23万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2017-12-31

项目摘要

项目成果

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中文摘要
翻译
多巴胺神经元对控制运动、情绪和认知功能非常重要,并在帕金森氏症等许多疾病中受到影响。有助于提高我们对疾病病因学的知识和新疗法的开发,将有助于更好地了解这些细胞在发育过程中最初是如何出生的。这个项目研究了脑膜在多巴胺开发和修复中的作用,并将确定相关的蛋白质和信号通路。
英文摘要
Dopamine neurons are important for the control of movement, emotion and cognitive function, and are affected in a number of disorders such as Parkinson’s disease. Instrumental in improving our knowledge of disease etiology and the development of new therapies will be a greater understanding of how these cells are initially born during development. This project examines the role of the brain’s meninges in dopamine development and repair and will identify proteins and signaling pathways involved.
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