Structural Characterisation of Long Non-Coding RNA bound Histone Modification Complexes
Structural Characterisation of Long Non-Coding RNA bound Histone Modification Complexes
批准号:
nhmrc : GNT1090408
负责人:
Dr Alastair Stewart
金额:
$30.94万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 --
中文摘要
癌症是一种与DNA的遗传和表观遗传变化相关的疾病。表观遗传学涉及DNA的外部变化,“打开”和“关闭”过程,以调节基因表达。该项目旨在为基于表观遗传的致癌作用中涉及的关键过程提供强有力的见解,从而为生产新型癌症诊断标志物和基于分子的治疗奠定基础。
英文摘要
Cancer is a disease associated with genetic and epigenetic changes of DNA. Epigenetics involves external changes to the DNA, switching processes “on” and “off”, to regulate gene expression. This project aims to provide powerful insight into key processes involved in epigenetic-based carcinogenesis, and thereby lay the foundation for producing novel cancer diagnostic markers and molecular based therapies.
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会议论文
ATP synthase: Regulation, antibiotics and mitochondrial disease
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批准号:nhmrc : GNT1159347
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项目类别:Career Development Fellowships
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资助金额:$43.7万
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财政年份:2019
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负责人:Dr Alastair Stewart
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依托单位:
The structural basis for promiscuity of drug binding to hERG K+ channels
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批准号:nhmrc : 1141974
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项目类别:Project Grants
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资助金额:$48.21万
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财政年份:2018
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负责人:Dr Alastair Stewart
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依托单位:
The structural basis for promiscuity of drug binding to hERG K+ channels
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批准号:nhmrc : GNT1141974
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项目类别:Project Grants
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资助金额:$71.3万
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财政年份:2018
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负责人:Dr Alastair Stewart
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依托单位:
Antibiotic peptides that inhibit ATP synthase
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批准号:nhmrc : 1146403
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项目类别:Project Grants
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资助金额:$31.33万
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财政年份:2018
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负责人:Dr Alastair Stewart
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依托单位:
Antibiotic peptides that inhibit ATP synthase
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批准号:nhmrc : GNT1146403
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项目类别:Project Grants
-
资助金额:$46.33万
-
财政年份:2018
-
负责人:Dr Alastair Stewart
-
依托单位:
Structural Characterisation of Long Non-Coding RNA bound Histone Modification Complexes
-
批准号:nhmrc : 1090408
-
项目类别:Early Career Fellowships
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资助金额:$21.4万
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财政年份:2015
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负责人:Dr Alastair Stewart
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依托单位:
海外基金